Impact of COVID-19 outbreak on patients with ST-segment elevation myocardial infarction (STEMI) in Turkey: results from TURSER study (TURKISH St-segment elevation myocardial infarction registry)
Yükleniyor...
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective We aimed to investigate both the impact of COVID-19 pandemic on ST-segment elevation myocardial infarction
(STEMI) admission, and demographic, angiographic, procedural characteristics, and in-hospital clinical outcomes of patients
with COVID-19 positive STEMI in Turkey.
Methods This was a multi-center and cross-sectional observational study. The study population included 1788 STEMI
patients from 15 centers in Turkey. The patients were divided into two groups: COVID-19 era (March 11st–May 15st, 2020;
n=733) or pre- COVID-19 era group (March 11st–May 15st, 2019; n=1055). Also, the patients in COVID-19 era were
grouped as COVID-19 positive (n=65) or negative (n=668).
Results There was a 30.5% drop in STEMI admission during COVID-19 era in comparison to pre-COVID-19 era. The
patients admitted to the medical centers during COVID-19 era had a longer symptom-to-frst medical contact time [120
(75–240) vs. 100 (60–180) minutes, p<0.001]. COVID-19 positive STEMI patients had higher thrombus grade and lower
left ventricular ejection fraction compared to COVID-19 negative patients. COVID-19 positive patients had higher mortality (28% vs. 6%, p<0.001) and cardiogenic shock (20% vs. 7%, p<0.001) rates compared with those without COVID-19.
Matching based on propensity scores showed higher mortality and high thrombus grade in STEMI patients who were infected
by SARS-COV-2 (each p<0.05).
Conclusions We detected signifcantly lower STEMI hospitalization rates and signifcant delay in duration of symptom
onset to frst medical contact in the context of Turkey during the COVID-19 outbreak. Moreover, high thrombus grade and
mortality were more common in COVID-19 positive STEMI patients.
Açıklama
WOS:000655937200001
PMID: 34050883
PMID: 34050883
Anahtar Kelimeler
COVID-19, SARS-CoV2, ST elevation myocardial infarction, Primary percutaneous coronary, Intervention, Mortality
Kaynak
Journal of Thrombosis and Thrombolysis
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
Early Access
Sayı
Künye
Kiris, T., Avcı, E., Ekin, T., Akgün, D.E., Tiryaki, M., Yidirim, A. ve diğerleri. (2021). Impact of COVID-19 outbreak on patients with ST-segment elevation myocardial infarction (STEMI) in Turkey: results from TURSER study (TURKISH St-segment elevation myocardial infarction registry). Journal of Thrombosis and Thrombolysis, Early access. 1-14.
