Multicenter Epidemiologic Study on Hepatocellular Carcinoma in Turkey

Basit Öğe Kaydı
dc.contributor.authorCan, Alper
dc.contributor.authorDogan, Erkan
dc.contributor.authorBayoglu, Ibrahim Vedat
dc.contributor.authorTatli, Ali Murat
dc.contributor.authorBesiroglu, Mehmet
dc.contributor.authorKocer, Murat
dc.contributor.authorDulger, Ahmet Cumhur
dc.date.accessioned2024-04-24T17:28:19Z
dc.date.available2024-04-24T17:28:19Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Hepatocellular cancer (HCC) is one of the important health problems in Turkey, being very common and highly lethal. The aim of this study was to determine clinical, demographic features and risk factors. Materials and Methods: Nine hundred and sixth-three patients with HCC from 13 cities in Turkey were included in this study. Results: Only 205 (21%) of the 963 patients were women, with a male: female predominance of 4.8:1 and a median age of 61 years. The etiologic risk factors for HCC were hepatitis B in 555 patients (57.6%), 453 (81%) in men, and 102 (19%) in women, again with male predominance, hepatitis C in 159 (16.5%), (14.9% and 22.4%, with a higher incidence in women), and chronic alcohol abuse (more than ten years) in 137 (14.2%) (16.8% and 4.9%, higher in males). The Child-Pugh score paralleled with advanced disease stage amd also a high level of AFP. Conclusions: According to our findings the viral etiology (hepatitis B and hepatitis C infections) in the Turkish population was the most important factor in HCC development, with alcohol abuse as the third risk factor. The Child-Pugh classification and AFP levels were determined to be important prognostic factors in HCC patients.en_US
dc.identifier.doi10.7314/APJCP.2014.15.6.2923
dc.identifier.endpage2927en_US
dc.identifier.issn1513-7368
dc.identifier.issue6en_US
dc.identifier.pmid24761926en_US
dc.identifier.scopus2-s2.0-84899844040en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage2923en_US
dc.identifier.urihttps://doi.org/10.7314/APJCP.2014.15.6.2923
dc.identifier.urihttps://hdl.handle.net/11468/20402
dc.identifier.volume15en_US
dc.identifier.wosWOS:000335651700087
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherAsian Pacific Organization Cancer Preventionen_US
dc.relation.ispartofAsian Pacific Journal of Cancer Preventionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHepatocellular Carcinomaen_US
dc.subjectEtiologic Factorsen_US
dc.subjectAlpha-Fetoproteinen_US
dc.subjectTurkeyen_US
dc.titleMulticenter Epidemiologic Study on Hepatocellular Carcinoma in Turkeyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu