The Biochemical and Histologic Effects of Adnexal Torsion and Early Surgical Intervention to Unwind Detorsion on Ovarian Reserve: An Experimental Study

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dc.contributor.authorOzler, Ali
dc.contributor.authorTurgut, Abdulkadir
dc.contributor.authorSoydinc, Hatice Ender
dc.contributor.authorSak, Muhammet Erdal
dc.contributor.authorEvsen, Mehmet Siddik
dc.contributor.authorAlabalik, Ulas
dc.contributor.authorBasarali, Mustafa Kemal
dc.date.accessioned2024-04-24T17:14:45Z
dc.date.available2024-04-24T17:14:45Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: The aim of the present study was to determine to what extent ovarian reserves are affected by ischemia-reperfusion injury, evaluating the number of growing follicles and the serum levels of the ovarian hormones. Study Design: Thirty female fertile adult Wistar albino rats, weighing 200 to 220 g, were previously numbered to randomization, and then randomly divided into 3 equal groups (n = 10): sham, torsion, and detorsion groups. In torsion and detorsion groups, bilateral adnexal torsion (3-hour ischemia) was carried out. Bilateral adnexal detorsion (3-hour reperfusion) was performed in the detorsion group. Results: The mean number of preantral and small antral follicles in detorsion group were lower than those of the sham group (P < .01). After torsion, anti-Mullerian hormone (AMH), estradiol, and inhibin B levels decreased significantly compared to the preoperative and postoperative periods (P = .003, P = .032, and P = .014, respectively). In detorsion group, only AMH levels were found to decrease significantly following the 3-hour ischemia and 3-hour reperfusion (P < .05). Conclusion: After adnexal torsion, a significant decrease in ovarian reserve has been detected for the first time in this study. Additionally, the results of this study suggest that conservative surgery alone is insufficient to protect ovarian reserve.en_US
dc.identifier.doi10.1177/1933719113485300
dc.identifier.endpage1355en_US
dc.identifier.issn1933-7191
dc.identifier.issn1933-7205
dc.identifier.issue11en_US
dc.identifier.pmid23585344
dc.identifier.scopus2-s2.0-84885677213
dc.identifier.scopusqualityQ1
dc.identifier.startpage1349en_US
dc.identifier.urihttps://doi.org/10.1177/1933719113485300
dc.identifier.urihttps://hdl.handle.net/11468/18178
dc.identifier.volume20en_US
dc.identifier.wosWOS:000325477900011
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofReproductive Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdnexal Torsionen_US
dc.subjectOvarian Reserveen_US
dc.subjectOvarian Folliclesen_US
dc.subjectAnti-Mullerian Hormoneen_US
dc.subjectInhibin Ben_US
dc.titleThe Biochemical and Histologic Effects of Adnexal Torsion and Early Surgical Intervention to Unwind Detorsion on Ovarian Reserve: An Experimental Studyen_US
dc.titleThe Biochemical and Histologic Effects of Adnexal Torsion and Early Surgical Intervention to Unwind Detorsion on Ovarian Reserve: An Experimental Study
dc.typeArticleen_US

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