The relationship between acute kidney injury and inflammation-based parameters and mortality in oncologic intensive care patients

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dc.authorid0000-0001-7657-3065en_US
dc.authorid0000-0002-7768-2455en_US
dc.authorid0000-0002-8101-2497en_US
dc.authorid0000-0002-7251-046Xen_US
dc.contributor.authorAydın, Emre E.
dc.contributor.authorKadiroǧlu, Ali Kemal
dc.contributor.authorYilmaz Aydin, Fatma
dc.contributor.authorKara, Ali Veysel
dc.date.accessioned2021-08-17T06:23:02Z
dc.date.available2021-08-17T06:23:02Z
dc.date.issued2020en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıklar Ana Bilim Dalıen_US
dc.descriptionWOS:000614471900004
dc.description.abstractBackground and Aims: Cancer patients are admitted to intensive care units (ICU) due to primary diseases, treatment-related conditions or comorbid diseases. Acute kidney injury (AKI) and infections appear to be factors affecting mortality and morbidity in ICU follow-up. Therefore, in our study, we investigated the effect of AKI and inflammation-based parameters on mortality in cancer patients admitted to the ICU. Materials and Methods: In this study, 386 patients diagnosed with malignancy hospitalized between 2010 and 2014 in Dicle University Medical Faculty Internal Medicine ICU were included. The study was designed retrospectively. The demographic characteristics and clinical information of the patients were obtained from the files. Subsequently, patients were classified as non-survivors (group 1) and survivors (group 2). Both groups were compared in terms of the presence and stage of AKI by KDIGO definition, neutrophil / lymphocyte ratio (NLR) and platelet / lymphocyte ratio (PLR). Results: Creatinine, CRP, neutrophil counts were found to be significantly higher and albumin, hemoglobin, platelet and lymphocyte counts were found to be lower in group 1 (n=276) compared to group 2 (n=110). Length of ICU was longer in group 2 patients. There was a positive correlation between mortality and KDIGO stages and NLR. Mortality rate was increased 1.9 fold in KDIGO stage 1, 2.3 fold in stage 2, 2.4 fold in stage 3 and 1.5 fold if NLR>5. There was no statistically significant relationship between PLR and mortality. Conclusion: The presence of AKI and elevated inflammation-based parameters were associated with mortality in oncologic patients admitted to the ICU.en_US
dc.identifier.citationAydın, E. E., Kadiroǧlu, A. K., Yilmaz, A. F. ve Kara, A. V. (2020). The relationship between acute kidney injury and inflammation-based parameters and mortality in oncologic intensive care patients. Journal of Critical and Intensive Care, 11(2), 50-54.en_US
dc.identifier.doi10.37678/dcybd.2020.2310
dc.identifier.endpage54en_US
dc.identifier.issn2717-6428
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85089845762
dc.identifier.scopusqualityQ4
dc.identifier.startpage50en_US
dc.identifier.trdizinid384943
dc.identifier.urihttp://www.jcritintensivecare.org/uploads/pdf/pdf_DCY_EN_272.pdf
dc.identifier.urihttps://hdl.handle.net/11468/7341
dc.identifier.volume11en_US
dc.identifier.wosWOS:000614471900004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorAydın, Emre E.
dc.institutionauthorKadiroǧlu, Ali Kemal
dc.institutionauthorYilmaz Aydin, Fatma
dc.institutionauthorKara, Ali Veysel
dc.language.isoenen_US
dc.publisherTurkish Society of Medical and Surgical Intensive Careen_US
dc.relation.ispartofJournal of Critical and Intensive Care
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcute kidney injuryen_US
dc.subjectCanceren_US
dc.subjectIntensive care uniten_US
dc.subjectMortalityen_US
dc.titleThe relationship between acute kidney injury and inflammation-based parameters and mortality in oncologic intensive care patientsen_US
dc.titleThe relationship between acute kidney injury and inflammation-based parameters and mortality in oncologic intensive care patients
dc.typeArticleen_US

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