Phytochemical characterization and biological activities of Inula viscosa L. Aiton: a promising plant from Turkey

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dc.contributor.authorEruygur, Nuraniye
dc.contributor.authorTuzcu, Nevin
dc.contributor.authorTugay, Osman
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.contributor.authorÇakır, Oğuz
dc.date.accessioned2024-04-24T16:24:45Z
dc.date.available2024-04-24T16:24:45Z
dc.date.issued2024
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümüen_US
dc.description.abstractThe methanol extract of Inula viscosa (IVM) was investigated for its antioxidant potential using the DPPH and ABTS radical scavenging as well as iron chelating assays (ICA). The total phenol (TPC) and flavonoid contents (TFC) of IVM were determined using the Folin-Ciocalteu and aluminum trichloride methods, respectively. Antimicrobial activity of different concentrations of I. viscosa methanol extract was investigated by disc diffusion and broth microdilution method. The IVM extract was found to be containing TPC (236.78 +/- 7.63 mg GAE/g) and TFC (94.36 +/- 1.86 mg QE/g). Antioxidant activity IC50 values for the DPPH, ABTS and ICA assays were found to be 277.7 +/- 3.68, 2.44 +/- 0.02, and 222.1 +/- 0.71 mu g/mL, respectively. The MIC values of the IVM on the tested microorganisms ranged from 0.48 to 7.81 mg/mL. Furthermore, IVM extract was demonstrated 18.32 +/- 1.37%, 23.06 +/- 1.05%, 4.72 +/- 0.13%, 15.13 +/- 0.37% and 37.64 +/- 4.02% inhibition against tyrosinase, alpha-amylase, alpha-glucosidase, AChE and BChE, respectively. In the results of LC-MS/MS analysis, acacetin, quercetin, chlorogenic acid and protocatechuic acid were determined as most dominant compounds. These findings suggested that this plant may be a natural resource for creating novel medicinal compounds.en_US
dc.identifier.citationEruygur, N., Tuzcu, N., Tugay, O., Yılmaz, M. A. ve Çakır, O. (2024). Phytochemical characterization and biological activities of Inula viscosa L. Aiton: a promising plant from Turkey. International Journal of Environmental Health Research, 1-14.
dc.identifier.doi10.1080/09603123.2024.2305215
dc.identifier.issn0960-3123
dc.identifier.issn1369-1619
dc.identifier.pmid38245842
dc.identifier.scopus2-s2.0-85182836311
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1080/09603123.2024.2305215
dc.identifier.urihttps://hdl.handle.net/11468/16840
dc.identifier.wosWOS:001146335800001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofInternational Journal of Environmental Health Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectInula viscosaen_US
dc.subjectAntimicrobialen_US
dc.subjectAntioxidanten_US
dc.subjectEnzyme inhibitionen_US
dc.subjectLc-Ms/Msen_US
dc.titlePhytochemical characterization and biological activities of Inula viscosa L. Aiton: a promising plant from Turkeyen_US
dc.titlePhytochemical characterization and biological activities of Inula viscosa L. Aiton: a promising plant from Turkey
dc.typeArticleen_US

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