Effect of flunixin meglumine or prostaglandin E2 treatment 15 days after breeding on fertility in Saanen does

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dc.contributor.authorCetin, Yunus
dc.contributor.authorKocamuftuoglu, Mesih
dc.contributor.authorOzyurtlu, Nihat
dc.contributor.authorKucukaslan, Ibrahim
dc.contributor.authorSendag, Sait
dc.contributor.authorWehrend, Axel
dc.date.accessioned2024-04-24T16:18:29Z
dc.date.available2024-04-24T16:18:29Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe objective of this study was to determine the effects of timely injections of flunixin meglumine (FM) or vaginal application of prostaglandin E2 (PgE(2)) on pregnancy, fertility, fecundity, and prolificacy rates in Saanen goats. One hundred and sixty-three nonlactating Saanen does were treated with a flugestone acetate (20 mg)-containing intravaginal sponge for 12 days. They also received eCG (400 IU) and a PGF(2 alpha) analogue (50 mu g) 10 days after progestagen priming. Does detected in estrus were mated and assigned randomly to one of three treatment groups. The PgE(2) group (N = 40) received PgE(2) (2.5 mg) intravaginally 15 days after mating. The FM group (N = 54) received flunixin meglumine (total dose, 100 mg) intramuscularly 15 days after mating. Flunixin meglumine was administered at 9:00 AM. Animals in the control group (N = 69) received no treatment. Pregnancy was diagnosed using transrectal ultrasonography (B-mode at 8 MHz) 30 days after mating. The pregnancy rate was significantly greater (P < 0.01) after 30 days in goats treated with PgE(2) and also in the control group than in those treated with FM (67.5%, 59.4%, and 42.5%, respectively). The pregnancy rate did not differ between the PgE(2) and the control group. The pregnancy and fertility rate were lowest in the FM group compared with the other groups. There was no significant difference in the prolificacy rate among experimental groups. In conclusion, our results showed that FM administration during a late luteal phase is detrimental to early pregnancy in goats. (C) 2014 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.theriogenology.2013.10.015
dc.identifier.endpage427en_US
dc.identifier.issn0093-691X
dc.identifier.issn1879-3231
dc.identifier.issue3en_US
dc.identifier.pmid24238401
dc.identifier.scopus2-s2.0-84891632965
dc.identifier.scopusqualityQ1
dc.identifier.startpage424en_US
dc.identifier.urihttps://doi.org/10.1016/j.theriogenology.2013.10.015
dc.identifier.urihttps://hdl.handle.net/11468/16122
dc.identifier.volume81en_US
dc.identifier.wosWOS:000330254400008
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTheriogenology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCyclooxygenasesen_US
dc.subjectFertilityen_US
dc.subjectCorpus Luteumen_US
dc.titleEffect of flunixin meglumine or prostaglandin E2 treatment 15 days after breeding on fertility in Saanen doesen_US
dc.titleEffect of flunixin meglumine or prostaglandin E2 treatment 15 days after breeding on fertility in Saanen does
dc.typeArticleen_US

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