Comparison of PA spine, lateral spine, and femoral BMD measurements to determine bone loss in ankylosing spondylitis

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dc.contributor.authorUlu, Mehmet Ali
dc.contributor.authorCevik, Remzi
dc.contributor.authorDilek, Banu
dc.date.accessioned2024-04-24T16:00:05Z
dc.date.available2024-04-24T16:00:05Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractTo evaluate bone loss in the early- and late-stage ankylosing spondylitis (AS) patients using posteroanterior (PA) and lateral lumbar and femoral bone mineral density (BMD) measurement methods. Eighty-six AS patients and 50 control subjects were enrolled. PA spine, lateral spine, and femur BMD values of patients and controls were measured. The presence of any syndesmophytes or compression fractures was determined. Patients were divided as early (< 10 years) and late stage (a parts per thousand yen10 years) according to the onset of the inflammatory pain. Mean PA spinal BMD was similar in patients and controls (p = 0.460). Femoral and lateral spine BMD values were significantly lower in patients (p = 0.012 and p = 0.001). When comparing early- and late-stage AS groups, mean PA spinal BMD was found to be lower in the early group (p = 0.005), while femoral and lateral spinal values were lower (although statistically not significant) in the late group. At least one compression fracture was present in 28 % of patients. Although not statistically significant, mean PA spinal BMD was higher in those with fractures. Femoral and lateral spinal BMD values were significantly lower in the fracture group (p = 0.034 and p = 0.004). Lateral spinal BMD values were significantly lower in patients with syndesmophytes (p = 0.004). Bone loss is increased in AS compared with control subjects. The BMD measurement at the lateral lumbar spine reflects bone loss and fracture risk better than PA spine and femoral measurements.en_US
dc.identifier.doi10.1007/s00296-012-2632-9
dc.identifier.endpage1711en_US
dc.identifier.issn0172-8172
dc.identifier.issn1437-160X
dc.identifier.issue7en_US
dc.identifier.pmid23274443
dc.identifier.scopus2-s2.0-84879693111
dc.identifier.scopusqualityQ1
dc.identifier.startpage1705en_US
dc.identifier.urihttps://doi.org/10.1007/s00296-012-2632-9
dc.identifier.urihttps://hdl.handle.net/11468/14367
dc.identifier.volume33en_US
dc.identifier.wosWOS:000321259500007
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofRheumatology International
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnkylosing Spondylitisen_US
dc.subjectOsteoporosisen_US
dc.subjectLateral Vertebral Bmden_US
dc.titleComparison of PA spine, lateral spine, and femoral BMD measurements to determine bone loss in ankylosing spondylitisen_US
dc.titleComparison of PA spine, lateral spine, and femoral BMD measurements to determine bone loss in ankylosing spondylitis
dc.typeArticleen_US

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