The importance of low visfatin values in osteoid osteoma patient: a prospective study
dc.authorid | 0000-0003-2149-8154 | en_US |
dc.contributor.author | Ulus, Sait Anıl | |
dc.contributor.author | Özkul, Emin | |
dc.date.accessioned | 2024-01-17T12:39:25Z | |
dc.date.available | 2024-01-17T12:39:25Z | |
dc.date.issued | 2023 | en_US |
dc.department | Dicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Ortopedi ve Travmatoloji Ana Bilim Dalı | en_US |
dc.description.abstract | Abstract. – OBJECTIVE: Visfatin is currently a cytokine that is extensively researched in the field of bone diseases. In this prospective study, we aimed to investigate the potential of serum visfatin levels as a biomarker for the diagnosis of osteoid osteoma. PATIENTS AND METHODS: This study included a cohort of 20 patients diagnosed with osteoid osteoma (Group 1) and 30 healthy individuals (Group 2). The age, gender, cyst sizes, and visfatin values of all participants were documented and analyzed. RESULTS: There was a significant difference in visfatin levels between the two groups. The median visfatin level in Group 1 was 6.13 ng/ml (IQR: 4.21-8.08), while in Group 2, it was 15.83 ng/ml (IQR: 11.11-20.6). The difference was statistically significant (p<0.000). The optimal cutoff value for visfatin was found to be 7.74 ng/ml, which had a 93% sensitivity and 78% specificity. An area under the curve of receiver operating characteristic (ROC) analysis of 0.85 indicates good diagnostic performance. CONCLUSIONS: Our study revealed a significant decrease in visfatin levels among patients diagnosed with osteoid osteomas in comparison to the healthy control group. The ROC analysis revealed that visfatin exhibited a commendable diagnostic capacity, indicating its potential utility as a biomarker for osteoid osteoma. | en_US |
dc.identifier.citation | Ulus, S. A. ve Özkul, E. (2023). The importance of low visfatin values in osteoid osteoma patient: a prospective study. European Review for Medical and Pharmacological Sciences, 27(23), 11543-11549. | en_US |
dc.identifier.doi | 10.26355/eurrev_202312_34592 | |
dc.identifier.endpage | 11549 | en_US |
dc.identifier.issn | 1128-3602 | |
dc.identifier.issue | 23 | en_US |
dc.identifier.pmid | 38095401 | |
dc.identifier.scopus | 2-s2.0-85179770168 | |
dc.identifier.scopusquality | Q2 | |
dc.identifier.startpage | 11543 | en_US |
dc.identifier.uri | https://www.europeanreview.org/wp/wp-content/uploads/11543-11549.pdf | |
dc.identifier.uri | https://hdl.handle.net/11468/13211 | |
dc.identifier.volume | 27 | en_US |
dc.identifier.wos | WOS:001159390600005 | |
dc.identifier.wosquality | N/A | |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | Scopus | |
dc.indekslendigikaynak | PubMed | |
dc.institutionauthor | Ulus, Sait Anıl | |
dc.institutionauthor | Özkul, Emin | |
dc.language.iso | en | en_US |
dc.publisher | Verduci Editore s.r.l | en_US |
dc.relation.ispartof | European Review for Medical and Pharmacological Sciences | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Visfatin | en_US |
dc.subject | Osteoid osteoma | en_US |
dc.subject | Biomarker | en_US |
dc.title | The importance of low visfatin values in osteoid osteoma patient: a prospective study | en_US |
dc.title | The importance of low visfatin values in osteoid osteoma patient: a prospective study | |
dc.type | Article | en_US |
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