Contribution of the peak exercise QT dispersion to the accuracy of an exercise test during the evaluation of coronary artery disease

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dc.contributor.authorÜlgen, MS
dc.contributor.authorKaradede, A
dc.contributor.authorAlan, S
dc.contributor.authorTemamogulari, AV
dc.contributor.authorKarabulut, A
dc.contributor.authorToprak, N
dc.date.accessioned2024-04-24T17:18:25Z
dc.date.available2024-04-24T17:18:25Z
dc.date.issued2000
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective - Regional defects in ventricle repolarization are extremely sensitive to ischaemia which can be measured as QT dispersion (QTd). We investigated the role of QTd calculated at the time of peak exercise during treadmill studies. Methods and results - Thirty-three women and eighty men, whose treadmill test results and coronary angiography studies had been examined, were divided into four groups according to the test results: 1)subjects with a negative treadmill test and without significant stenosis results in the angiography, were considered normal (N; n = 35); 2) subjects with both a positive exercise test and a significant presence of stenotic coronary arteries, were considered true positive (TP; n = 52); 3) subjects with a positive exercise test, but without significant stenosis results in the angiography, were considered false positive (FP; n = 14); 4) subjects with a negative treadmill study, despite significantly stenotic arteries, were considered false negative (FN; n = 12), All subjects were evaluated on the basis of age, significant ST-segment depression, peak heart rate, rest and peak exercise QT, and QpT (measured from the beginning of the QRS complex to the highest point of the T wave) dispersion, and corrected (QTcd, QpTcd) values for heart rate. The most significant differences were observed between the N and the TP groups in terms of QTd and QTcd (p < 0.01), with a higher correlation (r = 0.48). A significant relationship was also observed in terms of QpT and QpTcd values during peak exercise (p < 0.01). The sensitivity of the peak exercise QTcd and QTcd greater than or equal to 70 ms in determining coronary artery disease was found to be 74%. In cases of QTcd greater than or equal to 70 ms, in addition to ST-segment depression, the test was found to be less sensitive, but more specific at 96%. Conclusion - It suggests that when peak exercise QTd and QpTd values are taken into account, with the exception of the ST-segment depression, the accuracy of the exercise test will increase and false positive results will decrease.en_US
dc.identifier.doi10.2143/AC.55.6.2005764
dc.identifier.endpage339en_US
dc.identifier.issn0001-5385
dc.identifier.issue6en_US
dc.identifier.pmid11227833
dc.identifier.scopus2-s2.0-0034484907
dc.identifier.scopusqualityQ3
dc.identifier.startpage335en_US
dc.identifier.urihttps://doi.org/10.2143/AC.55.6.2005764
dc.identifier.urihttps://hdl.handle.net/11468/18773
dc.identifier.volume55en_US
dc.identifier.wosWOS:000166901600003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherActa Cardiologicaen_US
dc.relation.ispartofActa Cardiologica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectExercise Testen_US
dc.subjectQt Dispersionen_US
dc.subjectCoronary Artery Diseaseen_US
dc.titleContribution of the peak exercise QT dispersion to the accuracy of an exercise test during the evaluation of coronary artery diseaseen_US
dc.titleContribution of the peak exercise QT dispersion to the accuracy of an exercise test during the evaluation of coronary artery disease
dc.typeArticleen_US

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