Tuberculous and brucellosis meningitis differential diagnosis

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dc.contributor.authorErdem, Hakan
dc.contributor.authorSenbayrak, Seniha
dc.contributor.authorGencer, Serap
dc.contributor.authorHasbun, Rodrigo
dc.contributor.authorKarahocagil, Mustafa Kasim
dc.contributor.authorSengoz, Gonul
dc.contributor.authorKarsen, Hasan
dc.date.accessioned2024-04-24T16:18:30Z
dc.date.available2024-04-24T16:18:30Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: The Thwaites and Lancet scoring systems have been used in the rapid diagnosis of tuberculous meningitis (TBM). However, brucellar meningoencephalitis (BME) has similar characteristics with TBM. The ultimate aim of this study is to infer data to see if BME should be included in the differential diagnosis of TBM when these two systems suggest the presence of TBM. Method: BME and TBM patients from 35 tertiary hospitals were included in this study. Overall 294 adult patients with BME and 190 patients with TBM were enrolled. All patients involved in the study had microbiological confirmation for either TBM or BME. Finally, the Thwaites and Lancet scoring systems were assessed in both groups. Results: The Thwaites scoring system more frequently predicted BME cases (n = 292, 99.3%) compared to the TBM group (n = 182, 95.8%) (P = 0.017). According to the Lancet scoring system, the mean scores for BME and TBM were 9.43 +/- 1.71 and 11.45 +/- 3.01, respectively (P < 0.001). In addition, TBM cases were classified into probable category more significantly compared to BME cases, and BME cases were categorized into the possible category more frequently. Conclusions: When the Thwaites or Lancet scoring systems indicate TBM, brucellar etiology should also be taken into consideration particularly in endemic countries. (C) 2015 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.tmaid.2015.02.008
dc.identifier.endpage191en_US
dc.identifier.issn1477-8939
dc.identifier.issn1873-0442
dc.identifier.issue2en_US
dc.identifier.pmid25801665
dc.identifier.scopus2-s2.0-84926407993
dc.identifier.scopusqualityQ1
dc.identifier.startpage185en_US
dc.identifier.urihttps://doi.org/10.1016/j.tmaid.2015.02.008
dc.identifier.urihttps://hdl.handle.net/11468/16135
dc.identifier.volume13en_US
dc.identifier.wosWOS:000353741200014
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofTravel Medicine and Infectious Disease
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBrucellosisen_US
dc.subjectTuberculosisen_US
dc.subjectMeningitisen_US
dc.subjectDiagnosisen_US
dc.titleTuberculous and brucellosis meningitis differential diagnosisen_US
dc.titleTuberculous and brucellosis meningitis differential diagnosis
dc.typeArticleen_US

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