Occult hepatitis B infection in Turkish HIV-infected patients: A multicentre, retrospective, cross-sectional study, Schindler study

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dc.authorid0000-0003-2419-3436en_US
dc.contributor.authorÜnlü, Gülten
dc.contributor.authorYıldız, Yeşim
dc.contributor.authorÖren, Meryem Merve
dc.contributor.authorÇabalak, Mehmet
dc.contributor.authorMete, Özlem
dc.contributor.authorKömür, Süheyla
dc.contributor.authorYıldırım, Figen
dc.contributor.authorİnan, Dilara
dc.contributor.authorToplu, Sibel Altunışık
dc.contributor.authorAkhan, Sıla
dc.contributor.authorKaraşahin, Ömer
dc.contributor.authorKalkan, İrem Akdemir
dc.contributor.authorDemir, Yakup
dc.contributor.authorAyhan, Merve
dc.contributor.authorKaraoğlan, İlkay
dc.contributor.authorTaşova, Yeşim
dc.contributor.authorBayındır, Yaşar
dc.contributor.authorDal, Tuba
dc.contributor.authorÇelen, Mustafa Kemal
dc.date.accessioned2022-08-26T07:37:56Z
dc.date.available2022-08-26T07:37:56Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalıen_US
dc.descriptionWOS:000654928300001
dc.descriptionPMID: 33977603
dc.description.abstractObjective Occult hepatitis B infection (OHBI) appears to have a higher prevalence in populations at high risk for hepatitis B virus (HBV) infection with concomitant liver disease. The aim was to assess the prevalence of OHBI in a sample of human immunodeficiency virus -1 positive and HBV surface antigen-negative (HIV-1+/HBsAg-) Turkish patients. Methods Ten centres in Turkey were included in the study. Patients were selected on the basis of a power calculation with a known population size of HIV-positive patients and a reported prevalence of OHBI. Gender, age, occupation, place of residence, treatment and clinical status, and laboratory results, including immunodeficiency panel, antibody tests, hemogram, biochemistry, and coagulation studies were evaluated retrospectively. Results The number of HIV-infected patients followed in these centres was 3172 and the sample population numbered 278. All 278 were HBsAg negative. The mean age of the sample was 37.2 +/- 13.1 years and 235 (84.5%) were male. All but one patient (99.6%) had been treated with antiretroviral therapy. Of the 278 patients, 169 (60.6%) were positive for Anti-HBs and 125 (44.8%) were positive for Anti-HBc IgG. HIV RNA was detected in 203/278 (73%) of the patients. Four HBV DNA (1.4%) were diagnosed with OHBI. There was no significant difference in hemogram, hemoglobin or bilirubin concentrations in those with OHBI compared with the other patients. Conclusion In a representative sample of HIV+ patients from 10 Turkish centres, the prevalence of OHBI was found to be 1.4%. In HIV positive patients, it is important to identify those with OHBI for optimal clinical management and prognosis.en_US
dc.identifier.citationÜnlü, G., Yıldız, Y., Ören, M.M., Çabalak, M., Mete, Ö., Kömür, S. ve diğerleri. (2021). Occult hepatitis B infection in Turkish HIV-infected patients: A multicentre, retrospective, cross-sectional study, Schindler study. International Journal of Clinical Practice,75(9), 1-7. https://doi.org/10.1111/ijcp.14358en_US
dc.identifier.doi10.1111/ijcp.14358
dc.identifier.endpage7en_US
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.issue9en_US
dc.identifier.pmid33977603
dc.identifier.scopus2-s2.0-85106620811
dc.identifier.scopusqualityQ1
dc.identifier.startpage1en_US
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/epdf/10.1111/ijcp.14358
dc.identifier.urihttps://hdl.handle.net/11468/10263
dc.identifier.volume75en_US
dc.identifier.wosWOS:000654928300001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorDemir, Yakup
dc.institutionauthorÇelen, Mustafa Kemal
dc.language.isoenen_US
dc.publisherWiley-Hindawien_US
dc.relation.ispartofInternational Journal of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.titleOccult hepatitis B infection in Turkish HIV-infected patients: A multicentre, retrospective, cross-sectional study, Schindler studyen_US
dc.titleOccult hepatitis B infection in Turkish HIV-infected patients: A multicentre, retrospective, cross-sectional study, Schindler study
dc.typeArticleen_US

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