Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in patients with restless legs syndrome

Basit Öğe Kaydı
dc.contributor.authorHalac, G.
dc.contributor.authorKilic, E.
dc.contributor.authorCikrikcioglu, M. A.
dc.contributor.authorCelik, K.
dc.contributor.authorToprak-Erek, A.
dc.contributor.authorKeskin, S.
dc.contributor.authorGultepe, I
dc.date.accessioned2024-04-24T17:24:18Z
dc.date.available2024-04-24T17:24:18Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractOBJECTIVE: The aim of this study was to assess the predisposition for atherosclerosis in patients with RLS through serum sLOX-1 (serum Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1) measurements. BACKGROUND: Recent epidemiological studies have suggested an association of RLS with certain chronic conditions such as diabetes mellitus (DM), obesity, hypertension (HT), and hyperlipidemia. LOX-1 is expressed in endothelial cells, macrophages, and in smooth muscle cells under the effect of proatherogenic conditions. METHODS: This study was a prospective, cross-sectional, case-controlled. We measured the serum sLOX-1 levels in 37 restless legs syndrome patients and 38 controls. RESULTS: Serum sLOX-1 level was significantly lower in the patient group. The two groups were similar in glucose, HbA1c, creatinine, LDL cholesterol, TG, HDL, total protein, albumin, AST, ALT, GGT, ALP, HGB, HCT, MCV, transferrin saturation rate (TSR), ferritin, CRP, TSH, FT4, FT3, B12, and folic acid levels. Also the two groups were similar with respect to age at menarche, number of previous births, number of abortions and/or curettage, total duration of breastfeeding, percentage of patients in menopause, and age at menopause. CONCLUSION: Our results may suggest a lower atherosclerotic risk among RLS patients as compared to the general population (Tab. 3, Ref. 33). Text in PDF www.elis.sk.en_US
dc.identifier.doi10.4149/BLL_2016_063
dc.identifier.endpage320en_US
dc.identifier.issn0006-9248
dc.identifier.issn1336-0345
dc.identifier.issue6en_US
dc.identifier.pmid27546362
dc.identifier.scopus2-s2.0-85014849674
dc.identifier.scopusqualityQ2
dc.identifier.startpage316en_US
dc.identifier.urihttps://doi.org/10.4149/BLL_2016_063
dc.identifier.urihttps://hdl.handle.net/11468/19596
dc.identifier.volume117en_US
dc.identifier.wosWOS:000378300700004
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherComenius Univen_US
dc.relation.ispartofBratislava Medical Journal-Bratislavske Lekarske Listy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectRestless Legs Syndromeen_US
dc.subjectAtherosclerosisen_US
dc.subjectSlox-1en_US
dc.titleSerum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in patients with restless legs syndromeen_US
dc.titleSerum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in patients with restless legs syndrome
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu