The association between cellular morphological changes in peripheral blood smear and complications in pediatric burn cases

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dc.contributor.authorBozkurt, Mehmet
dc.contributor.authorKuvat, Samet Vasfi
dc.contributor.authorKapi, Emin
dc.contributor.authorKarakol, Percin
dc.contributor.authorOzel, Abdulkadir
dc.contributor.authorBaykan, Halit
dc.date.accessioned2024-04-24T17:27:44Z
dc.date.available2024-04-24T17:27:44Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractBACKGROUND Mortality and morbidity in burn cases can be reduced with early diagnosis. Many markers are used for early diagnosis of burn complications like sepsis. In this current study, the relationship between numerical/morphologic granulocyte abnormalities and complications was investigated in pediatric burns. It was aimed to introduce histopathologic marker(s) for burn-related complications. METHODS Thirty-two pediatric burn cases hospitalized between December 2006 and December 2009 were included in the study. A total of 192 complete blood count and peripheral blood smear results were analyzed comparatively. Findings were used to identify any correlation among white blood cell count and peripheral blood smear changes (the appearance of immature granular cells, toxic granulation, purple granules and Dohle bodies) and complications such as bacteriemia, sepsis, wound infections, severe anemia, and graft failure. RESULTS White blood cell count changes and the appearance of immature granular cells were not suitable for use as a diagnostic marker for complications. Nevertheless, there was a statistically significant correlation between the appearance of toxic granulation, purple granules and Dohle bodies and subsequent complications (p: < 0.0001, 0.041, 0.001, respectively). CONCLUSION Toxic granulation, purple granules and Dohle bodies appear to be helpful in predicting burn-related complications. Therefore, peripheral blood smear is a suitable test for predicting future complications.en_US
dc.identifier.doi10.5505/tjtes.2011.13911
dc.identifier.endpage132en_US
dc.identifier.issn1306-696X
dc.identifier.issue2en_US
dc.identifier.pmid21644090
dc.identifier.scopus2-s2.0-79955449377
dc.identifier.scopusqualityQ3
dc.identifier.startpage128en_US
dc.identifier.urihttps://doi.org/10.5505/tjtes.2011.13911
dc.identifier.urihttps://hdl.handle.net/11468/20173
dc.identifier.volume17en_US
dc.identifier.wosWOS:000288968900007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isotren_US
dc.publisherTurkish Assoc Trauma Emergency Surgeryen_US
dc.relation.ispartofUlusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDohle Bodyen_US
dc.subjectCellular Morphological Changesen_US
dc.subjectBlood Smearen_US
dc.subjectPurple Granuleen_US
dc.subjectToxic Granulationen_US
dc.subjectBurnen_US
dc.titleThe association between cellular morphological changes in peripheral blood smear and complications in pediatric burn casesen_US
dc.titleThe association between cellular morphological changes in peripheral blood smear and complications in pediatric burn cases
dc.typeArticleen_US

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