Early detection of macular and peripapillary changes with spectralis optical coherence tomography in patients with prediabetes

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dc.contributor.authorSahin, Muhammed
dc.contributor.authorSahin, Alparslan
dc.contributor.authorKilinc, Faruk
dc.contributor.authorKaraalp, Umit
dc.contributor.authorYuksel, Harun
dc.contributor.authorOzkurt, Zeynep Gursel
dc.contributor.authorTurkcu, Fatih Mehmet
dc.date.accessioned2024-04-24T17:07:46Z
dc.date.available2024-04-24T17:07:46Z
dc.date.issued2018
dc.departmentDicle Üniversitesien_US
dc.description.abstractPurpose: To compare the retina ganglion cell complex (GCC) layer and peripapillary nerve fibre layer thickness (pRNFL) in patients with prediabetes and healthy subjects analysed by spectral domain optical coherence tomography (SD-OCT). Methods: This cross-sectional and comparative study included prediabetic patients and healthy subjects. All participants underwent SD-OCT measurement of pRNFL thickness, and GCC thickness. Results: A total of 30 eyes of the 30 patients with prediabetes and 30 eyes of 30 controls were included. The overall calculated pRNFL thicknesses were similar between the prediabetic and control subjects. The GCC thickness was significantly lower in all quadrants of the inner macula, and outer nasal quadrant in the prediabetes group when compared to the control group. Conclusion: Our study demonstrated that inner macular GCC thickness was significantly thinner in prediabetic subjects. As a result neurodegeneration may play role in the thinning of GCC.en_US
dc.identifier.doi10.1080/13813455.2017.1361450
dc.identifier.endpage79en_US
dc.identifier.issn1381-3455
dc.identifier.issn1744-4160
dc.identifier.issue1en_US
dc.identifier.pmid28780883
dc.identifier.scopus2-s2.0-85026863145
dc.identifier.scopusqualityQ1
dc.identifier.startpage75en_US
dc.identifier.urihttps://doi.org/10.1080/13813455.2017.1361450
dc.identifier.urihttps://hdl.handle.net/11468/16970
dc.identifier.volume124en_US
dc.identifier.wosWOS:000425063500010
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofArchives of Physiology and Biochemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCentral Macular Thicknessen_US
dc.subjectDiabetes Mellitusen_US
dc.subjectMacular Ganglion Cell Complexen_US
dc.subjectPeripapillary Retinal Nerve Fibre Layeren_US
dc.subjectPrediabetesen_US
dc.titleEarly detection of macular and peripapillary changes with spectralis optical coherence tomography in patients with prediabetesen_US
dc.titleEarly detection of macular and peripapillary changes with spectralis optical coherence tomography in patients with prediabetes
dc.typeArticleen_US

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