Severe scorpion envenomation in children: Management in pediatric intensive care unit

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dc.contributor.authorBoşnak, Mehmet
dc.contributor.authorYilmaz, Hayri Levent
dc.contributor.authorEce, Aydın
dc.contributor.authorYildizdas, Dincer
dc.contributor.authorYolbas, Ilyas
dc.contributor.authorKocamaz, Halil
dc.contributor.authorKaplan, Metin
dc.date.accessioned2024-04-24T17:14:37Z
dc.date.available2024-04-24T17:14:37Z
dc.date.issued2009
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Scorpion envenomation is a common public health problem worldwide and children are at greater risk of developing severe cardiac, respiratory and neurological complications. The aim of this study was to evaluate the effects of antivenin and/or prazosin use on prognosis of scorpion-envenomed children admitted to pediatric intensive care unit (PICU). Methods: The standardized medical records of 45 children hospitalized with severe scorpion sting in PICU were retrospectively evaluated. General characteristics of the children, clinical and laboratory findings, treatment approaches and prognosis were evaluated. Results: The mean age of the patients were 6.1 +/- 4.1 years ranging between 4 month and 15 years. Male to female ratio was 1.8. Thirty-three (71.1%) cases of scorpion stings came from rural areas. Twenty-six (57.8%) of the patients were stung by Androctonus crassicauda. The most common sting localization was the foot-leg (55.6%). The mean duration from the scorpion sting to hospital admission was 4.5 +/- 2.6 hours. The most common findings at presentation were cold extremities (95.5%), excessive sweating (91.1%) and tachycardia (77.7%). The mean leukocyte count, and serum levels of glucose, lactate dehydrogenase, creatine phosphokinase and international normalized ratio were found above the normal ranges. Prazosin was used in all patients, dopamine in 11 (24.4%) and Na-nitroprusside in 4 (8.8%) patients. Two children died (4.4%) due to pulmonary oedema. These children, in poor clinical status at hospital admission, needed mechanical ventilation, and death occurred despite use of antivenin and prazosin in both of them. Conclusion: The current management of children with severe scorpion envenomation consists of administration of specific antivenom and close surveillance in a PICU, where vital signs and continuous monitoring enable early initiation of therapy for life-threatening complications. The aggressive medical management directed at the organ system specifically can be effective. Our data indicated that when admission to hospital is late, the beneficial effect of antivenom and/or prazosin is questionable in severe scorpion stings.en_US
dc.identifier.doi10.1177/0960327109350667
dc.identifier.endpage728en_US
dc.identifier.issn0960-3271
dc.identifier.issn1477-0903
dc.identifier.issue11en_US
dc.identifier.pmid19812121
dc.identifier.scopus2-s2.0-70450215235
dc.identifier.scopusqualityQ2
dc.identifier.startpage721en_US
dc.identifier.urihttps://doi.org/10.1177/0960327109350667
dc.identifier.urihttps://hdl.handle.net/11468/18096
dc.identifier.volume28en_US
dc.identifier.wosWOS:000271860400006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofHuman & Experimental Toxicology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChildrenen_US
dc.subjectPicuen_US
dc.subjectScorpion Stingsen_US
dc.subjectPrognosisen_US
dc.subjectAntiveninen_US
dc.subjectPrazosinen_US
dc.titleSevere scorpion envenomation in children: Management in pediatric intensive care uniten_US
dc.titleSevere scorpion envenomation in children: Management in pediatric intensive care unit
dc.typeArticleen_US

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