Metabolic changes and serum ghrelin level in patients with psoriasis

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dc.authorid0000-0001-6162-3250en_US
dc.authorid0000-0001-8405-7730en_US
dc.contributor.authorUçak, Haydar
dc.contributor.authorDemir, Betül
dc.contributor.authorÇiçek, Demet
dc.contributor.authorErden, İlker
dc.contributor.authorAydın, Süleyman
dc.contributor.authorDertlioǧlu, Selma Bakar
dc.contributor.authorArıca, Mustafa
dc.date.accessioned2024-04-03T06:37:05Z
dc.date.available2024-04-03T06:37:05Z
dc.date.issued2014en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Deri ve Zührevi Hastalıklar Ana Bilim Dalıen_US
dc.description.abstractBackground. Serum ghrelin levels may be related to metabolic and clinical changes in patients with psoriasis. Objective. This study was performed to determine the possible effects of serum ghrelin in patients with psoriasis. Methods. The study population consisted of 25 patients with plaque psoriasis. The patients were questioned with regard to age, gender, age of onset, duration of disease, height, weight, and body mass index (BMI). In addition, fasting blood sugar, triglyceride, cholesterol levels, insulin, and ghrelin levels were measured. Results. The mean serum ghrelin level was 45.41 ± 22.41 in the psoriasis group and 29.92 ± 14.65 in the healthy control group. Serum ghrelin level was significantly higher in the psoriasis group compared with the controls (P=0.01). The mean ghrelin level in patients with a lower PASI score was significantly higher than in those with a higher PASI score (P=0.02). Conclusion. The present study was performed to determine the effects of ghrelin in psoriasis patients. We found a negative correlation between severity of psoriasis and ghrelin level. Larger and especially experimental studies focusing on correlation of immune system-ghrelin levels and severity of psoriasis may be valuable to clarify the etiopathogenesis of the disease.en_US
dc.identifier.citationUçak, H., Demir, B., Çiçek, D., Erden, İ., Aydın, S., Dertlioğlu, S. B. ve diğerleri. (2014). Metabolic changes and serum ghrelin level in patients with psoriasis. Dermatology Research and Practice, 2014, 1-7.en_US
dc.identifier.doi10.1155/2014/175693en_US
dc.identifier.endpage7en_US
dc.identifier.issn1687-6113
dc.identifier.pmid25587268en_US
dc.identifier.scopus2-s2.0-84929371291en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://www.hindawi.com/journals/drp/2014/175693/
dc.identifier.urihttps://hdl.handle.net/11468/13796
dc.identifier.volume2014en_US
dc.identifier.wosWOS:000215105500002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorUçak, Haydar
dc.institutionauthorArıca, Mustafa
dc.language.isoenen_US
dc.publisherHindawi Limiteden_US
dc.relation.ispartofDermatology Research and Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGhrelinen_US
dc.subjectMetabolic changesen_US
dc.titleMetabolic changes and serum ghrelin level in patients with psoriasisen_US
dc.typeArticleen_US

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