Tc-99m nanocolloid scintigraphic imaging of intracranial meningeal extramedullary hematopoiesis in a patient with idiopathic myelofibrosis

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dc.contributor.authorKaya, Halil
dc.contributor.authorCerci, Sevim Sureyya
dc.date.accessioned2024-04-24T15:59:40Z
dc.date.available2024-04-24T15:59:40Z
dc.date.issued2006
dc.departmentDicle Üniversitesien_US
dc.description.abstractMeningeal extramedullary hematopoiesis (EMH) is a rare finding in idiopathic myelofibrosis. Intracranial EMH is typically asymptomatic and sites are usually found by chance. Diagnosis of EMH is difficult, based on clinical circumstances and the use of different diagnostic imaging modalities, such as CT, MRI or radionuclide imaging. We present a case with intracranial medullary hematopoiesis due to idiopathic myelofibrosis diagnosed with Tc-99m nanocolloid scintigraphy. Cranium SPECT images that were performed with Tc-99m nanocolloid showed increased radiotracer uptake in the bilateral parietal, bilateral frontal and left occipital bones and especially in falx cerebri of sinus sagittalis superior. In Tc-99m MDP bone scintigraphy, increased osteoblastic activity in the left frontal and parietal bones, in shoulders, knee and ankle joints, and in both metatarsal bones were seen. After gadodiamid injection, T1 weighted MRI showed diffuse contrast increased in the meningeal areas surrounding the brain. A biopsy of the mass revealed extramedullary hematopoiesis composed of erythroblasts, mature and immature myeloid cells, and megakaryocytes. It was deduced that these described foci of EMH.en_US
dc.identifier.doi10.1007/BF03026823
dc.identifier.endpage568en_US
dc.identifier.issn0914-7187
dc.identifier.issue8en_US
dc.identifier.pmid17134026
dc.identifier.scopus2-s2.0-33751434175
dc.identifier.scopusqualityQ2
dc.identifier.startpage565en_US
dc.identifier.urihttps://doi.org/10.1007/BF03026823
dc.identifier.urihttps://hdl.handle.net/11468/14202
dc.identifier.volume20en_US
dc.identifier.wosWOS:000241880700011
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherJapanese Society Nuclear Medicineen_US
dc.relation.ispartofAnnals of Nuclear Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMeningeal Extramedullary Hematopoiesisen_US
dc.subjectIdiopathic Myelofibrosisen_US
dc.subjectTc-99m Nanocolloid Scintigraphyen_US
dc.titleTc-99m nanocolloid scintigraphic imaging of intracranial meningeal extramedullary hematopoiesis in a patient with idiopathic myelofibrosisen_US
dc.titleTc-99m nanocolloid scintigraphic imaging of intracranial meningeal extramedullary hematopoiesis in a patient with idiopathic myelofibrosis
dc.typeArticleen_US

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