The investigation of lipid peroxidation, anti-oxidant levels and some hematological parameters in sheep naturally infested with Wohlfahrtia magnifica larvae

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dc.contributor.authorIpek, Duygu Neval Sayin
dc.contributor.authorSaki, Cem Ecmel
dc.contributor.authorCay, Mehmet
dc.date.accessioned2024-04-24T16:18:37Z
dc.date.available2024-04-24T16:18:37Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractWohlfahrtia magnifica is the main agent of traumatic myiasis in many central and eastern European countries as well as in the Mediterranean basin and Asian countries. The present study was aimed to investigate the effect of myiasis infestation on lipid peroxidation, antioxidant levels and several hematological parameters in the sheep naturally infested with W. magnifica larvae. A total of 38 sheep, including 19 awassi sheep naturally infested with W. magmfica larvae and 19 clinically healthy awassi sheep, were studied. The infected animals were divided into three groups depending on the number of larvae (Group 1: <50 larvae: Group 2: 50-100 larvae; Group 3: >100 larvae). In blood samples, red blood cell counts, hemoglobin, hematocrit concentration and white blood cell, neutrophil, lymphocyte, eosinophil, basophil counts, plasma malondialdehyde, erythrocyte glutathione levels and erythrocyte glutathione peroxidase activity were studied. The results revealed a marked decrease in red blood cell counts and hemoglobin concentrations along with a significant increase in white blood cell and neutrophil counts. The elevation in plasma malondialdehyde levels, a function of lipid peroxidation, established a significant difference between the control group and groups 2, 3. Decreased activity of erythrocyte glutathione peroxidase was found significant in the control group and all parasitemia. We conclude that in natural infestations with W. magnifica, as in infestation with Lucilia cuprina, there is a notable increase in inflammatory activities resulting from the movements, secretions, and toxins of the larvae and form the toxins secreted by the bacteria - which leads to an impression of anemia - and that the tissue injury results in an increase in level of free radicals in the organism. (C) 2011 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipScientific Research Council of Dicle University [DU 08-61-76]en_US
dc.description.sponsorshipThis research was financially supported the Scientific Research Council of Dicle University (Project No: DU 08-61-76). Permission for the present study was obtained from the Ethic Committee for Animal Experiments of Firat University.en_US
dc.identifier.doi10.1016/j.vetpar.2011.12.018
dc.identifier.endpage118en_US
dc.identifier.issn0304-4017
dc.identifier.issn1873-2550
dc.identifier.issue1-2en_US
dc.identifier.pmid22245072
dc.identifier.scopus2-s2.0-84860697178
dc.identifier.scopusqualityQ1
dc.identifier.startpage112en_US
dc.identifier.urihttps://doi.org/10.1016/j.vetpar.2011.12.018
dc.identifier.urihttps://hdl.handle.net/11468/16196
dc.identifier.volume187en_US
dc.identifier.wosWOS:000304799300017
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofVeterinary Parasitology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectWohlfahrtia Magnificaen_US
dc.subjectAntioxidantsen_US
dc.subjectMdaen_US
dc.subjectHematological Parametersen_US
dc.subjectSheepen_US
dc.titleThe investigation of lipid peroxidation, anti-oxidant levels and some hematological parameters in sheep naturally infested with Wohlfahrtia magnifica larvaeen_US
dc.titleThe investigation of lipid peroxidation, anti-oxidant levels and some hematological parameters in sheep naturally infested with Wohlfahrtia magnifica larvae
dc.typeArticleen_US

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