Multicenter hospital-based prospective surveillance study of bacterial agents causing meningitis and seroprevalence of different serogroups of Neisseria meningitidis, Haemophilus influenzae Type B, and Streptococcus pneumoniae during 2015 to 2018 in Turkey

dc.authorid0000-0002-0760-5681en_US
dc.contributor.authorCeyhan, Mehmet
dc.contributor.authorÖzsürekçi, Yasemin
dc.contributor.authorBaşaranoglu, Sevgen Tanır
dc.contributor.authorGürler, Nezahat G.
dc.contributor.authorSalı, Enes
dc.contributor.authorEmiroglu, Melike
dc.contributor.authorÖz, Fatma Nur
dc.contributor.authorBelet, Nurşen M.
dc.contributor.authorDuman, Murat
dc.contributor.authorUlusoy, Emel
dc.contributor.authorKurugöl, Zafer
dc.contributor.authorTezer, Hasan
dc.contributor.authorParlakay, Aslınur Özkaya
dc.contributor.authorDinleyici, Ener Cagri
dc.contributor.authorÇelik, Ümit Sizmaz
dc.contributor.authorÇelebi, Solmaz
dc.contributor.authorÖner, Ahmet Faik
dc.contributor.authorSolmaz, Mehmet Ali
dc.contributor.authorKarbuz, Adem
dc.contributor.authorHatipoglu, Nevin
dc.contributor.authorDevrim, İlker
dc.contributor.authorCaglar, İlknur
dc.contributor.authorBozdemir, Şefika Elmas
dc.contributor.authorKocabaş, Emine
dc.contributor.authorGündeşli·oğlu, Özlem Özgür
dc.contributor.authorSütçü, Murat
dc.contributor.authorAkcan, Özge Metin
dc.contributor.authorKuyucu, Necdet
dc.contributor.authorAktar, Fesih
dc.contributor.authorKara, Soner Sertan
dc.contributor.authorAkışoğlu, Havva Özlem Altay
dc.contributor.authorTuygun, Nilden
dc.contributor.authorUslu, Zeynep Diyar Tamburaci
dc.contributor.authorÖncel, Eda Karadag
dc.contributor.authorBayhan, Cihangül
dc.contributor.authorCengiz, Ali Bülent
dc.date.accessioned2021-07-12T13:13:36Z
dc.date.available2021-07-12T13:13:36Z
dc.date.issued2020en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.descriptionWOS:000551068100003
dc.descriptionPMID: 32213620
dc.description.abstractThe etiology of bacterial meningitis in Turkey changed after the implementation of conjugated vaccines against Streptococcus pneumoniae and Haemophilus influenzae type b (Hib) in the Turkish National Immunization Program (NIP). Administration of Hib vaccine and PCV-7 (7-valent pneumococcal conjugate vaccine) was implemented in NIP in 2006 and 2009, respectively. In 2011, PCV-7 was replaced with PCV-13. Meningococcal vaccines have not yet been included in Turkish NIP. This prospective study comprised 27 hospitals located in seven regions of Turkey and represented 45% of the population. Children aged between 1 month and 18 years who were hospitalized with suspected meningitis were included. Cerebrospinal fluid (CSF) samples were collected, and bacterial identification was made according to the multiplex PCR assay results. During the study period, 994 children were hospitalized for suspected meningitis, and Hib (n = 3, 2.4%), S. pneumoniae (n = 33, 26.4%), and Neisseria meningitidis (n = 89, 71%) were detected in 125 samples. The most common meningococcal serogroup was MenB. Serogroup W comprised 13.9% (n = 5) and 7.5% (n = 4) of the meningococci in 2015 to 2016 and 2017 to 2018, respectively. Serogroup C was not detected. There were four deaths in the study; one was a pneumococcus case, and the others were serogroup B meningococcus cases. The epidemiology of meningococcal diseases has varied over time in Turkey. Differing from the previous surveillance periods, MenB was the most common serogroup in the 2015-to-2018 period. Meningococcal epidemiology is so dynamic that, for vaccination policies, close monitoring is crucial.en_US
dc.identifier.citationCeyhan, M., Özsürekçi, Y., Başaranoǧlu, S. T., Gürler, N. G., Salı, E., Emiroǧlu, M. ve diğerleri. (2020). Multicenter hospital-based prospective surveillance study of bacterial agents causing meningitis and seroprevalence of different serogroups of Neisseria meningitidis, Haemophilus influenzae Type B, and Streptococcus pneumoniae during 2015 to 2018 in Turkey. mSphere, 5(2), 00060-20.en_US
dc.identifier.doi10.1128/MSPHERE.00060-20en_US
dc.identifier.issn2379-5042
dc.identifier.issue2en_US
dc.identifier.pmid32213620en_US
dc.identifier.scopus2-s2.0-85082454357en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage00060-20en_US
dc.identifier.urihttps://journals.asm.org/doi/10.1128/mSphere.00060-20
dc.identifier.urihttps://hdl.handle.net/11468/7226
dc.identifier.volume5en_US
dc.identifier.wosWOS:000551068100003
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAktar, Fesih
dc.language.isoenen_US
dc.publisherAmerican Society for Microbiologyen_US
dc.relation.ispartofmSphereen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEpidemiologyen_US
dc.subjectHiben_US
dc.subjectMeningitisen_US
dc.subjectN. meningitidisen_US
dc.subjectS. pneumoniaeen_US
dc.subjectSurveillanceen_US
dc.subjectTurkeyen_US
dc.titleMulticenter hospital-based prospective surveillance study of bacterial agents causing meningitis and seroprevalence of different serogroups of Neisseria meningitidis, Haemophilus influenzae Type B, and Streptococcus pneumoniae during 2015 to 2018 in Turkeyen_US
dc.typeArticleen_US

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