Real-life data on the comorbidities in spondyloarthritis from our multicenter nationwide registry: BioStar

dc.contributor.authorCay, H. Fatih
dc.contributor.authorMelikoglu, Meltem Alkan
dc.contributor.authorYurdakul, Fatma Gul
dc.contributor.authorBoduee, Hatice
dc.contributor.authorAtaman, Sebnem
dc.contributor.authorCapkin, Erhan
dc.contributor.authorGurer, Gulcan
dc.date.accessioned2024-04-24T17:24:43Z
dc.date.available2024-04-24T17:24:43Z
dc.date.issued2023
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjectives: Considering that the comorbid situations during the management of Spondyloarthritis (SpA) have been underlined in several recommendations, the main objective of this study was to evaluate the comorbid conditions of Turkish patients with SpA.Patients and methods: This cross-sectional observational study was conducted with 1,242 SpA patients (844 males, 398 females; mean age: 43.9 +/- 11.0 years; range, 19 to 81 years) diagnosed according to the modified New York criteria for ankylosing spondylitis or the Assessment of SpondyloArthritis International Society (ASAS) criteria. The patient data were collected from the Biologic and targeted Synthetic antirheumatic drugs Registry (BioStar) between February 1, 2019, and December 29, 2020. Clinical and demographic data, including, age, sex, disease duration, body mass index (BMI), pain, patient's global assessment, physician's global assessment, Bath Ankylosing Spondylitis Disease Activity Index, Ankylosing Spondylitis Disease Activity Score, Bath Ankylosing Spondylitis Functional Index, Bath Ankylosing Spondylitis Metrology Index, and Maastricht Enthesitis Score, were recorded. Comorbid conditions were recorded by filling out a questionnaire according to the clinical history or medical records. Charlson Comorbidity Index and Rheumatic Disease Comorbidity Index scores were calculated from the gathered comorbidity information.Results: Nine hundred thirteen patients had radiographic axial SpA, 153 had nonradiographic axial SpA, and 176 had peripheral SpA. The most common comorbidities were hypertension (HT) (n=167, 13.4%), diabetes mellitus (DM) (n=83, 6.7%), thyroid disorders (n=64, 5.6%), and depression (n=61, 4.9%). The comorbidities and the calculated comorbidity indices were significantly higher in females, in those with a BMI >25 kg/m2, and those over 60 years of age. No relationship was found between smoking and alcohol use and comorbidities. A significantly higher prevalence of HT and DM in peripheral SpA patients and a lower prevalence of thyroid disorders in radiographic axial SpA patients were observed.Conclusion: The most commonly reported comorbidities were HT, DM, thyroid disorders, and depression in SpA patients according to the BioStar database. The frequency of comorbidities and composite comorbidity scores were higher among females, older (>60 years) patients, and overweight (BMI >25 kg/m2) patients.en_US
dc.description.sponsorshipTurkish League Against Rheumatism (TLAR)en_US
dc.description.sponsorshipThis investigation is financially supported by Turkish League Against Rheumatism (TLAR) .en_US
dc.identifier.doi10.46497/ArchRheumatol.2023.9793
dc.identifier.endpage346en_US
dc.identifier.issn2618-6500
dc.identifier.issue3en_US
dc.identifier.pmid38046248
dc.identifier.scopus2-s2.0-85170627011
dc.identifier.scopusqualityQ3
dc.identifier.startpage333en_US
dc.identifier.urihttps://doi.org/10.46497/ArchRheumatol.2023.9793
dc.identifier.urihttps://hdl.handle.net/11468/19806
dc.identifier.volume38en_US
dc.identifier.wosWOS:000866443500001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTurkish League Against Rheumatismen_US
dc.relation.ispartofArchives of Rheumatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCharlson Comorbidity Indexen_US
dc.subjectComorbiditiesen_US
dc.subjectRheumatic Disease Comorbidity Indexen_US
dc.subjectSpondyloarthritisen_US
dc.subjectBiostaren_US
dc.titleReal-life data on the comorbidities in spondyloarthritis from our multicenter nationwide registry: BioStaren_US
dc.titleReal-life data on the comorbidities in spondyloarthritis from our multicenter nationwide registry: BioStar
dc.typeArticleen_US

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