Elastography to assess the effect of varicoceles on testes: a prospective controlled study

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dc.contributor.authorDede, O.
dc.contributor.authorTeke, M.
dc.contributor.authorDaggulli, M.
dc.contributor.authorUtangac, M.
dc.contributor.authorBas, O.
dc.contributor.authorPenbegul, N.
dc.date.accessioned2024-04-24T17:11:25Z
dc.date.available2024-04-24T17:11:25Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractVaricoceles are the most common and treatable cause of male infertility. The pathophysiology of varicoceles primarily includes elevated temperature, adrenal hormone reflux, gonadotoxic metabolite reflux, altered testicular blood flow, antisperm antibody formation and oxidative stress. The diagnosis of a varicocele is mainly clinical. However, a Doppler ultrasound is used to obtain clinical data and to more accurately measure testicular size. Acoustic radiation force impulse (ARFI) is an additional technique to simultaneously show different areas with different densities in a colour-coded image and a B-mode or greyscale image. This can be used for structural analysis of testicular tissue and has become an additional method for detecting pathologic tissue alterations. We enrolled 30 patients who had clinically diagnosed with left varicoceles and male infertility (Group 1). All patients were evaluated by history taking, physical examination, a spermiogram and an endocrine profile. Thirty control patients (Group 2) were randomly chosen from patients who had applied to an andrology clinic for infertility; their physical examinations and laboratory results showed normal findings. Mean elastography results were significantly different between the groups, and significantly lower in patients who had varicoceles. The relationship between hormonal profiles and elastography parameters was calculated as statistically significant negative correlations between FSH and elasticity. Additionally, a negative correlation was determined between varicocele grade and elasticity of testes. In conclusion, our prospective study showed that ARFI imaging may be more useful than palpation for determining early damage of testicular structure by varicoceles.en_US
dc.identifier.doi10.1111/and.12440
dc.identifier.endpage261en_US
dc.identifier.issn0303-4569
dc.identifier.issn1439-0272
dc.identifier.issue3en_US
dc.identifier.pmid26011193
dc.identifier.scopus2-s2.0-84959920550
dc.identifier.scopusqualityQ1
dc.identifier.startpage257en_US
dc.identifier.urihttps://doi.org/10.1111/and.12440
dc.identifier.urihttps://hdl.handle.net/11468/17495
dc.identifier.volume48en_US
dc.identifier.wosWOS:000372497600003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAndrologia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectElastographyen_US
dc.subjectScrotal Ultrasounden_US
dc.subjectVaricoceleen_US
dc.titleElastography to assess the effect of varicoceles on testes: a prospective controlled studyen_US
dc.titleElastography to assess the effect of varicoceles on testes: a prospective controlled study
dc.typeArticleen_US

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