The effect of transarterial chemoembolization therapy on survival in patients with non-resectable hepatocellular carcinoma: Single-center study results

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dc.authorid0000-0001-9659-6053en_US
dc.authorid0000-0001-8346-9477en_US
dc.authorid0000-0002-2475-7804en_US
dc.contributor.authorKolu, Mehmet
dc.contributor.authorDere, Osman
dc.contributor.authorSönmez, Süleyman
dc.date.accessioned2024-03-04T13:08:06Z
dc.date.available2024-03-04T13:08:06Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalıen_US
dc.description.abstractBackground and Aim: This study was designed to investigate the tumor response and effect of drug-eluting transarterial chemoembolization (DEB-TACE) treatment on survival in patients diagnosed with hepatocel-lular carcinoma (HCC). Materials and Methods: The records of 40 patients who underwent DEB-TACE between March 2018 and November 2020 were retrospec-tively analyzed. Follow-up included abdominal computed tomography and measurement of serum albumin, bilirubin, prothrombin time, and al-pha-fetoprotein values. The treatment response was evaluated using the European Association for the Study of the Liver criteria. Results: A total of 70 TACE sessions were performed in the 40 study patients with HCC. The etiology was chronic hepatitis B virus (n=32), secondary biliary cirrhosis (n=2), cryptogenic (n=2), or chronic hepatitis C virus (n=4). Based on the TACE response, complete response was observed in 22 patients, a partial response in 8 patients, and progression in 10 patients. Liver transplantation was performed for 4 patients who had a complete response. The formation of new nodules was observed in 8 patients during the follow-up period. In all, 29 patients survived and 11 died. Conclusion: The findings of this study suggest that DEB-TACE had a positive effect on the survival of patients diagnosed with HCC who could not be treated surgically.en_US
dc.identifier.citationKolu, M., Dere, O. ve Sönmez, S. (2021). The effect of transarterial chemoembolization therapy on survival in patients with non-resectable hepatocellular carcinoma: Single-center study results. Kare Publishing, 2(3), 102-106.en_US
dc.identifier.doi10.14744/hf.2021.2021.0029
dc.identifier.endpage106en_US
dc.identifier.issn2757-7392
dc.identifier.issue3en_US
dc.identifier.pmid35784908
dc.identifier.scopus2-s2.0-85164306466
dc.identifier.scopusqualityQ3
dc.identifier.startpage102en_US
dc.identifier.urihttps://hepatologyforum.org/storage/upload/pdfs/1631881398-en.pdf
dc.identifier.urihttps://hdl.handle.net/11468/13498
dc.identifier.volume2en_US
dc.identifier.wosWOS:000863551100004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKolu, Mehmet
dc.language.isoenen_US
dc.publisherKare Publishingen_US
dc.relation.ispartofHepatology Forum
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChronic liver diseaseen_US
dc.subjectHepatocellular carcinomaen_US
dc.subjectTransarterial chemoembolizationen_US
dc.titleThe effect of transarterial chemoembolization therapy on survival in patients with non-resectable hepatocellular carcinoma: Single-center study resultsen_US
dc.titleThe effect of transarterial chemoembolization therapy on survival in patients with non-resectable hepatocellular carcinoma: Single-center study results
dc.typeArticleen_US

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