Immunohistochemical analysis of CD31, CD36, and CD44 antigens in human omentum

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dc.contributor.authorYildirim, A
dc.contributor.authorAkkus, M
dc.contributor.authorNergiz, Y
dc.contributor.authorYuruker, S
dc.date.accessioned2024-04-24T17:37:31Z
dc.date.available2024-04-24T17:37:31Z
dc.date.issued2004
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: Milky spots in the human omental tissue are known to be consisting of lymphocytes, macrophages and mast cells. Our goal was to evaluate the relationship of lymphoid cells and macrophages with vasculature and stromal components. Methods: In this study we examined the biopsy specimens obtained from the adult patients whom were operated for different purposes in the General Surgery Department of Dicle University Hospital, Ankara, Turkey. We used CD31 as an endothelial cell marker, CD36 which is known to react with microvascular endothelium and adipocytes, and CD44 which is a hyaluronic acid receptor using an indirect immunoperoxidase technique. Results: We observed that CD31 was mainly reactive with vascular endothelial cells and platelets, CD36 was reactive with microvascular endothelium and adipocytes and CD44 was mainly expressed by the endothelial cells of high endothelial venules, fibroblasts in stromal compartments and by large mononuclear cells. Conclusion: We determined the structural and immunophenotypic features of omental lymphoid tissue components stressing vascular and stromal elements, and we briefly discussed the significance of the expression of these molecules in the determined locations.en_US
dc.identifier.endpage312en_US
dc.identifier.issn0379-5284
dc.identifier.issue3en_US
dc.identifier.pmid15048167
dc.identifier.scopus2-s2.0-1842738668
dc.identifier.scopusqualityQ2
dc.identifier.startpage308en_US
dc.identifier.urihttps://hdl.handle.net/11468/20980
dc.identifier.volume25en_US
dc.identifier.wosWOS:000220890700007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSaudi Med Jen_US
dc.relation.ispartofSaudi Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleImmunohistochemical analysis of CD31, CD36, and CD44 antigens in human omentumen_US
dc.titleImmunohistochemical analysis of CD31, CD36, and CD44 antigens in human omentum
dc.typeArticleen_US

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