A novel echocardiographic method as an indicator of endothelial dysfunction in patients with coronary slow flow

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dc.contributor.authorSimsek, H.
dc.contributor.authorSahin, M.
dc.contributor.authorGunes, Y.
dc.contributor.authorAkdag, S.
dc.contributor.authorAkil, M. A.
dc.contributor.authorAkyol, A.
dc.contributor.authorGumrukcuoglu, H. A.
dc.date.accessioned2024-04-24T17:33:11Z
dc.date.available2024-04-24T17:33:11Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractBACKGROUND: To improve clinical outcomes, noninvasive imaging modalities have been proposed to measure and monitor atherosclerosis. Endothelial dysfunction is considered the first stage in the development of atherosclerosis. Brachial artery flow-mediated dilatation (FMD) has been impaired in patients with coronary slow flow (CSF). Recently, color M-mode derived propagation velocity of descending thoracic aorta (aortic propagation velocity-AVP) was shown to be an ultrasonographic marker for atherosclerosis. AIM: To assess endothelial function in patients with CSF and the correlation of AVP with FMD. MATERIALS AND METHODS: FMD and AVP were measured in 90 patients with CSF and 39 patients having normal coronary arteries (NCA) detected by coronary angiography. RESULTS: Compared to patients with normal coronary arteries patients having CSF had significantly lower AVP (39.1 +/- 8.4 vs. 53.7 +/- 12.7 cm/s, p < 0.001) and FMD (5.6 +/- 3.2 vs. 17.6 +/- 4.4 %, p < 0.001) measurements. There were significant correlations between AVP and FMD (r = 0.524, p < 0.001). CONCLUSIONS: Transthoracic echocardio-graphic determination of color M-mode propagation velocity of descending aorta is a simple practical method and correlates well with coronary slow flow and brachial endothelial function.en_US
dc.identifier.endpage693en_US
dc.identifier.issn1128-3602
dc.identifier.issue5en_US
dc.identifier.pmid23543453
dc.identifier.scopus2-s2.0-84878564640
dc.identifier.scopusqualityQ2
dc.identifier.startpage689en_US
dc.identifier.urihttps://hdl.handle.net/11468/20509
dc.identifier.volume17en_US
dc.identifier.wosWOS:000319225900014
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectColor M-Modeen_US
dc.subjectCoronary Slow Flowen_US
dc.subjectEndothelial Functionen_US
dc.subjectFlow Mediated Dilatationen_US
dc.subjectPropagation Velocityen_US
dc.titleA novel echocardiographic method as an indicator of endothelial dysfunction in patients with coronary slow flowen_US
dc.titleA novel echocardiographic method as an indicator of endothelial dysfunction in patients with coronary slow flow
dc.typeArticleen_US

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