Non-functioning adrenal incidentalomas are associated with higher hypertension prevalence and higher risk of atherosclerosis

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dc.contributor.authorTuna, Mazhar Muslum
dc.contributor.authorImga, Narin Nasiroglu
dc.contributor.authorDogan, Bercem Aycicek
dc.contributor.authorYilmaz, Fatma Meric
dc.contributor.authorTopcuoglu, Canan
dc.contributor.authorAkbaba, Gulhan
dc.contributor.authorBerker, Dilek
dc.date.accessioned2024-04-24T16:10:39Z
dc.date.available2024-04-24T16:10:39Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractIntroduction Adrenal incidentalomas (AIs) have been associated with an increased incidence of several cardiovascular risk factors. The aim of this study was to investigate plasma adiponectin, leptin, resistin, homocysteine, high sensitive C-reactive protein levels, and carotid intima media thickness (CIMT) in patients with non-functioning AI (NFAI). Materials and methods This study included data from 28 patients with NFAI (Group 1) and 41 controls (Group 2). Of the patients, 50 were female and 19 were male, and the mean age was 46.7 (range 37-65) years. Results There were no significant differences between Group 1 and 2 in terms of age, sex, or BMI. Hypertension prevalence was significantly higher in the NFAI group than in the control group (p = 0.01). Both groups had similar lipid, blood glucose, homocysteine, uric acid, high-sensitivity CRP levels. Adiponectin, leptin, and resistin levels were similar in both groups. CIMTs were significantly higher in the NFAI group. Conclusion There is increasing evidence that several cardiometabolic risk factors occur with higher prevalence in non-functioning adrenal incidentaloma patients compared to age-matched healthy subjects. In our study, hypertension prevalence and CIMT were higher in the NFAI group. Serum adipokine levels were similar for both groups.en_US
dc.description.sponsorshipAnkara Numune Training and Research Hospitalen_US
dc.description.sponsorshipThis work was partially supported by Grants from Ankara Numune Training and Research Hospital.en_US
dc.identifier.doi10.1007/s40618-014-0106-5
dc.identifier.endpage768en_US
dc.identifier.issn1720-8386
dc.identifier.issue8en_US
dc.identifier.pmid24923898
dc.identifier.scopus2-s2.0-84907328308
dc.identifier.scopusqualityQ1
dc.identifier.startpage765en_US
dc.identifier.urihttps://doi.org/10.1007/s40618-014-0106-5
dc.identifier.urihttps://hdl.handle.net/11468/15004
dc.identifier.volume37en_US
dc.identifier.wosWOS:000342063200010
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Endocrinological Investigation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdrenal Incidentalomasen_US
dc.subjectAdipocytokineen_US
dc.subjectCarotid Intima Media Thicknessen_US
dc.subjectNon-Functioning Adrenal Incidentalomaen_US
dc.titleNon-functioning adrenal incidentalomas are associated with higher hypertension prevalence and higher risk of atherosclerosisen_US
dc.titleNon-functioning adrenal incidentalomas are associated with higher hypertension prevalence and higher risk of atherosclerosis
dc.typeArticleen_US

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