Evaluation of cutaneous palpebral anthrax

dc.contributor.authorTekin, Recep
dc.contributor.authorAri, Seyhmus
dc.contributor.authorDal, Tuba
dc.contributor.authorKaya, Safak
dc.contributor.authorKortak, Mehmet Zeki
dc.contributor.authorDursun, Birgul
dc.contributor.authorDayan, Saim
dc.date.accessioned2024-04-24T17:20:35Z
dc.date.available2024-04-24T17:20:35Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractContext: Anthrax is a rare disease caused by Bacillus anthracis. Antrax is zoonotic disease and is often encountered in persons engaged in animal husbandry. Cutaneous anthrax is approximately 95% of anthrax in humans. Palbebral involvement is rare. Objective: In this study, we aimed to evaluate the clinical presentation, diagnosis and treatment of cases with cutaneous palpebral anthrax. Methods: In this study, the patients diagnosed of cutaneous palpebral anthrax between January 2000 and December 2012, were investigated and evaluated, retrospectively. Cutaneous palpebral anthrax was diagnosed by the presence of typical anthrax lesion and/or observation of gram-positive encapsulated bacilli in gram prepations and/or culture positive of samples taken from lesions. In the cases who were culture-negative and without bacilli in gram-staining, the diagnosis was based on the presence of characteristic clinical presentation with a history of severe scarring formation, swelling, black eschar and positive response to the treatment. Results: A total of 21 patients with cutaneous palpebral anthrax admitted to the two hospitals between January 2000 and December 2012. Eight patients were male (38.1%) and 13 patients were female (61.9%), and the mean age was 31 +/- 21.2 (range 1-82 years). The most common symptoms on admission to the hospital were swelling and redness on the skin. Periorbital lesions were in the right eye in 14 cases and the most common eyelid involvement was seen in upper eyelid with 15 cases. The diagnosis was based on isolation of bacteria in five (23.8%) cases, detection of gram-positive bacilli in direct examination of characteristic lesion material in six (28.5%) cases. Ten (47.7%) cases were diagnosed by the characteristic appearance of the lesion. Malignant pustule was seen in all of our patients and seven cases (33.4%) had malignant edema. In the treatment, penicilin was used for 10 (47.7%) cases, ampicillin-sulbactam for five (23.8%) cases and, ciprofloxacin for three (14.3%) cases. Cicatricial ectropion was observed in 10 (47.7%) patients, lagophthalmos developed in four (19%) patients, and corneal scar in two (9.5%) patients. The distribution of the cases did not differ by the year but showed a density in the months from July to September (62.7%). Conclusion: Early diagnosis and high dose antibiotic treatment can facilitate the treatment and prevent development of eyelid complications including cicatricial ectropion, corneal scars and palpebral symphysis. Prolonged follow-up is necessary in patients who develop complications and surgical intervention.en_US
dc.identifier.doi10.3109/15569527.2013.781620
dc.identifier.endpage298en_US
dc.identifier.issn1556-9527
dc.identifier.issn1556-9535
dc.identifier.issue4en_US
dc.identifier.pmid23566172
dc.identifier.scopus2-s2.0-84883146170
dc.identifier.scopusqualityQ3
dc.identifier.startpage294en_US
dc.identifier.urihttps://doi.org/10.3109/15569527.2013.781620
dc.identifier.urihttps://hdl.handle.net/11468/19141
dc.identifier.volume32en_US
dc.identifier.wosWOS:000323527300007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofCutaneous and Ocular Toxicology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnthraxen_US
dc.subjectCutaneousen_US
dc.subjectEctropionen_US
dc.subjectPalpebralen_US
dc.titleEvaluation of cutaneous palpebral anthraxen_US
dc.titleEvaluation of cutaneous palpebral anthrax
dc.typeArticleen_US

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