Evaluation of choroidal thickness in psoriasis using optical coherence tomography

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dc.contributor.authorTurkcu, Fatih Mehmet
dc.contributor.authorSahin, Alparslan
dc.contributor.authorYuksel, Harun
dc.contributor.authorAkkurt, Meltem
dc.contributor.authorUcmak, Derya
dc.contributor.authorCinar, Yasin
dc.contributor.authorYildirim, Adnan
dc.date.accessioned2024-04-24T16:02:11Z
dc.date.available2024-04-24T16:02:11Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe purpose of this study was to evaluate choroidal thickness (CT) in patients with psoriasis using enhanced depth imaging optical coherence tomography (EDI-OCT) and to determine its relationship with psoriasis activity indices. In this prospective study, EDI-OCT images were obtained in consecutive patients with psoriasis and in age-gender-matched healthy individuals. Comprehensive ophthalmic examination and EDI-OCT evaluation were performed. CT was measured in the subfoveal area. Correlation analyses were performed to identify the relationship of the CT with disease duration and clinical disease activity score. In total, 65 individuals were evaluated in this study, 35 with psoriasis and 30 controls. The mean disease duration of the patients with psoriasis was 15.7 +/- 8.8 years (0.3-34 years). There was no difference between groups with respect to age and gender (p = 0.695 and p = 0.628, respectively). Five of the 35 patients with psoriasis had anterior uveitis. None of the patients with psoriasis had signs of posterior uveitis. CT was significantly higher in the psoriasis group than that of control subjects (p < 0.001). The mean central foveal thickness was comparable between groups (p = 0.672). There was also no significant correlation between EDI-OCT, disease activity score, and disease duration (p < 0.05). Choroidal thickness is increased in psoriasis patients. Large serial and comparative studies are necessary to evaluate EDI-OCT, an examination that may be helpful in understanding the effects of psoriasis on the eye and its pathophysiology.en_US
dc.identifier.doi10.1007/s10792-016-0212-9
dc.identifier.endpage854en_US
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue6en_US
dc.identifier.pmid26956606
dc.identifier.scopus2-s2.0-84960092223
dc.identifier.scopusqualityQ2
dc.identifier.startpage851en_US
dc.identifier.urihttps://doi.org/10.1007/s10792-016-0212-9
dc.identifier.urihttps://hdl.handle.net/11468/14677
dc.identifier.volume36en_US
dc.identifier.wosWOS:000388211300012
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPsoriasisen_US
dc.subjectChoroidal Thicknessen_US
dc.subjectUveitisen_US
dc.titleEvaluation of choroidal thickness in psoriasis using optical coherence tomographyen_US
dc.titleEvaluation of choroidal thickness in psoriasis using optical coherence tomography
dc.typeArticleen_US

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