Green synthesis and characterization of selenium nanoparticles (Se NPs) from the skin (testa) of Pistacia vera L. (Siirt pistachio) and investigation of antimicrobial and anticancer potentials
Yükleniyor...
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer Science and Business Media
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Metallic nanoparticles created by ecologically friendly synthesis processes are becoming increasingly useful in a variety of
applications. Because of their strong bioactive component qualities, biocompatible architectures, high stability, and low toxicity, green-produced selenium nanoparticles are particularly signifcant materials for various medicinal applications. Plants
include a wealth of essential phytochemicals with therapeutic and medical capabilities. Pistachio vera L. (Siirt pistachio) is
a seasonal fruit that is frequently consumed for its nutritional worth and health advantages. However, the outer colored skin
of the P. vera (Siirt pistachio) fruit, which is not consumed, contains many biologically active compounds. In this study,
plant-mediated synthesis of selenium nanoparticles (SeNPs) was successfully accomplished after adding the sodium selenite
solution to the aqueous extract of P. vera colored skin waste. The synthesized Se NPs were characterized with UV–Vis,
transmission electron microscopy (TEM), dynamic light scattering (DLS), zeta distribution, atomic force microscope (AFM),
Fourier transform infrared spectrum (FTIR), thermogravimetric (TGA) and diferential thermal analysis, X-ray difraction
(XRD), and energy-dispersive X-ray spectrum (EDX). Biogenic Pistacia vera (PV) PV-SeNPs were also tested for their ability to suppress the development of various pathogenic bacteria and cancerous cell lines. The UV-visible (UV–Vis) spectra
revealed an absorption peak at 325 nm, which refected the surface plasmon band. The signifcant selenium signal on the EDX
spectrum at 1.5 keV confrmed the creation of Se NPs. The presence of several peaks on the FTIR spectrum of the aqueous
extract of Pv and the nanoparticles indicated the presence of some important functional groups such as amines, carbonyl
compounds, and phenols, which are important in facilitating the process of capping and bioreduction, as well as conferring
stability to nanoparticles. The TEM microphotographs revealed that the nanoparticles were highly distributed, had a spherical
morphological form, and were monodisperse below 10 nm. Biogenic Pv-SeNPs exhibited similar antimicrobial activity as
standard antibiotics. However, it was determined that the cytotoxic activity of Se-NPs against cancer cell lines was quite high
depending on the dose and time. As a result, the Pv-SeNPs are likely to be extremely benefcial in the pharmaceutical and
cosmetic sectors, as well as in the food and cosmetic industries, in producing antimicrobial and/or anticancer medications.
Açıklama
Anahtar Kelimeler
Antipathogenic activity, Biosynthesis, Cytotoxic activity, Nanomedicine, Pistacia vera L. (Siirt pistachio), SeNPS
Kaynak
Biomass Conversion and Biorefinery
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
Article in Press
Sayı
Künye
Baran, M. F., Keskin, C., Baran, A., Kurt, K., Polat, İ., Eftekhari, A. ve diğerleri. (2023). Green synthesis and characterization of selenium nanoparticles (Se NPs) from the skin (testa) of Pistacia vera L. (Siirt pistachio) and investigation of antimicrobial and anticancer potentials. Biomass Conversion and Biorefinery, Article in Press.
