Serum Levels of Lipids, Lipoproteins and Paraoxonase Activity in Pre-eclampsia

dc.contributor.authorDemir, B.
dc.contributor.authorDemir, S.
dc.contributor.authorAtamer, Y.
dc.contributor.authorGuven, S.
dc.contributor.authorAtamer, A.
dc.contributor.authorKocyigit, Y.
dc.contributor.authorHekimoglu, A.
dc.date.accessioned2024-04-24T17:14:43Z
dc.date.available2024-04-24T17:14:43Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractSerum paraoxonase 1 (PON1) activity and the oxidation of lipoproteins were investigated in 35 women with preeclampsia and in 35 healthy control women with normal pregnancies. Blood pressure, body mass index (BMI), serum levels of total cholesterol, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein (LDL), apolipoprotein A1 (ApoA1), apolipoprotein B (ApoB) and lipoprotein (a) (Lp[a]), and PON1 activity were assessed. There were no significant between-group differences in subject age, gestational age at diagnosis of preeclampsia, BMI, serum total cholesterol, triglycerides, LDL and ApoB levels. Mean systolic and diastolic blood pressures and serum Lp(a) were significantly higher in subjects with pre-eclampsia than in controls. Mean serum HDL, ApoA1 and PON1 activity were significantly lower in subjects with pre-eclampsia compared with controls. In conclusion, lipids and oxidized lipoproteins may play important roles in the pathogenesis of preeclampsia.en_US
dc.identifier.doi10.1177/147323001103900430
dc.identifier.endpage1431en_US
dc.identifier.issn0300-0605
dc.identifier.issn1473-2300
dc.identifier.issue4en_US
dc.identifier.pmid21986144
dc.identifier.scopus2-s2.0-80052242146
dc.identifier.scopusqualityQ2
dc.identifier.startpage1427en_US
dc.identifier.urihttps://doi.org/10.1177/147323001103900430
dc.identifier.urihttps://hdl.handle.net/11468/18160
dc.identifier.volume39en_US
dc.identifier.wosWOS:000295654500030
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofJournal of International Medical Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPre-Eclampsiaen_US
dc.subjectLipidsen_US
dc.subjectLipoproteinsen_US
dc.subjectParaoxonase Activityen_US
dc.titleSerum Levels of Lipids, Lipoproteins and Paraoxonase Activity in Pre-eclampsiaen_US
dc.titleSerum Levels of Lipids, Lipoproteins and Paraoxonase Activity in Pre-eclampsia
dc.typeArticleen_US

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