Incidence, clinical findings and management of intraoperative floppy iris syndrome associated with tamsulosin

Basit Öğe Kaydı
dc.contributor.authorKeklikci, Ugur
dc.contributor.authorIsen, Kenan
dc.contributor.authorUnlu, Kaan
dc.contributor.authorCelik, Yusuf
dc.contributor.authorKarahan, Mine
dc.date.accessioned2024-04-24T17:11:40Z
dc.date.available2024-04-24T17:11:40Z
dc.date.issued2009
dc.departmentDicle Üniversitesien_US
dc.description.abstractTo determine the risk ratios and incidence of intraoperative floppy iris syndrome (IFIS) during cataract surgery in patients using tamsulosin, and to assess management strategies for IFIS. We performed a non-randomized, observational, prospective study, in which 594 eyes of 579 patients undergoing cataract surgery were enrolled. Surgeons were masked to the patients' drug history. Usage or non-usage of tamsulosin, duration of tamsulosin use, presence or absence of IFIS, management of IFIS and intraoperative complications were recorded in the patients' theatre notes. Twelve of 15 (80%) IFIS patients were taking systemic tamsulosin. Twelve of 23 (52%) patients using tamsulosin showed features of IFIS. The odds ratios (ORs) and relative risk (RR) ratios show strong positive correlations between tamsulosin use and IFIS. The ORs and RR ratios and the 95% confidence intervals (CIs) are as follows: OR 206.5 (95% CI 50.9-836.5); RR 99.3 (95% CI 30.0-327.8). There were no statistically significant differences between patients with or without IFIS, who were using tamsulosin, in terms of age or duration of tamsulosin use (p > 0.05). Seven eyes (46.6%) with IFIS were successfully managed with epinephrine. Eight eyes (53.4%) with IFIS needed iris hooks. Patients using tamsulosin appear to be at high risk of IFIS during cataract surgery. The occurrence of IFIS may not be affected by duration of tamsulosin use or age. Epinephrine may be effective in approximately 50% of eyes with IFIS. The iris hook procedure represents an effective management strategy in IFIS.en_US
dc.identifier.doi10.1111/j.1755-3768.2008.01246.x
dc.identifier.endpage309en_US
dc.identifier.issn1755-375X
dc.identifier.issue3en_US
dc.identifier.pmid18384448
dc.identifier.scopus2-s2.0-65349148580
dc.identifier.scopusqualityQ1
dc.identifier.startpage306en_US
dc.identifier.urihttps://doi.org/10.1111/j.1755-3768.2008.01246.x
dc.identifier.urihttps://hdl.handle.net/11468/17663
dc.identifier.volume87en_US
dc.identifier.wosWOS:000265251400013
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWiley-Blackwell Publishing, Incen_US
dc.relation.ispartofActa Ophthalmologica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCataract Surgeryen_US
dc.subjectEpinephrineen_US
dc.subjectFloppy Irisen_US
dc.subjectIris Hooken_US
dc.subjectTamsulosinen_US
dc.titleIncidence, clinical findings and management of intraoperative floppy iris syndrome associated with tamsulosinen_US
dc.titleIncidence, clinical findings and management of intraoperative floppy iris syndrome associated with tamsulosin
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu