Comparison of Presenting Features and Three-year Disease Course in Turkish Patients with Behcet Uveitis Who Presented in the Early 1990s and the Early 2000s
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Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Informa Healthcare
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose: To compare Behcet uveitis patients who presented in the 1990s and 2000s. Methods: Records of 170 patients seen in 1990-1994 and 258 patients seen in 2000-2004 were reviewed. Presenting features were analyzed in the whole cohort. Uveitis attacks, vision, complications, and immunomodulatory treatment (IMT) were compared in patients with 3-year follow-up. Results: Posterior segment involvement was less common, visual acuity was better, and more patients received IMT before referral in the 2000s. Follow-up revealed no significant difference in number of uveitis attacks in the first 3 years. Less eyes lost useful vision, no patient became legally blind, and fewer severe ocular complications occurred in the 2000s. IMT was started within 3 months in more patients and interferon alfa-2a was used only in the latter study period. Conclusions: The findings suggest a milder disease at referral, lower rate of severe complications, and a better 3-year visual outcome in patients who presented in the early 2000s.
Açıklama
Anahtar Kelimeler
Behcet Uveitis, Immunomodulatory Treatment, Interferon Alfa-2a, Prognosis, Visual Outcome
Kaynak
Ocular Immunology and Inflammation
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
20
Sayı
6
