Factors affecting morbidity and mortality in gangrenous cholecystitis

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dc.contributor.authorGirgin, S.
dc.contributor.authorGedik, E.
dc.contributor.authorTacyildiz, I. H.
dc.contributor.authorAkguen, Y.
dc.contributor.authorBac, B.
dc.contributor.authorUysal, E.
dc.date.accessioned2024-04-24T17:33:58Z
dc.date.available2024-04-24T17:33:58Z
dc.date.issued2006
dc.departmentDicle Üniversitesien_US
dc.description.abstractIntroduction : Gangrenous cholecystitis is a serious complication of acute cholecystitis. Male gender, older age, leukocytosis, cardio-vascular diseases and diabetes were reported as factors that increase the risk of gangrenous cholecystitis. The aim our study was to determine variables affecting morbidity and mortality as well as to define the independent risk factors in Gangrenous Cholecystitis. Methods : Fifty three patients who had been treated for Gangrenous Cholecystitis were reviewed. The variables are defined as follows : age, gender, systemic diseases, Mannheim Peritonitis index, aspartate aminotransferase, alanine aminotransferase, white blood cell count and type of surgery. In order to determine the independent risk factors that might affect morbidity and mortality in Gangrenous Cholecystitis, we made use of multivariate logistic regression analysis. Results : The independent risk factors affecting on morbidity were age (P = 0.037), existing systemic disease (P 0.047) and >= 29 Mannheim Peritonitis index (P = 0.008), and the independent risk factors affecting on mortality were age (P = 0.046), white blood cell count (P = 0.035). Pre-operative and post-operative third day aspartate aminotransferase and alanine aminotransferase average values were compared, there was a significant difference (P < 0.0001, P < 0.0001 respectively). Conclusions : We found that older age, >= 29 Mannheim Peritonitis index and existence of systemic diseases were independent risk factors affecting morbidity. Older age and lower of white blood cell count were independent risk factors affecting mortality. We believe that further comprehensive studies, involving prospective, multi-center and a large number of patients, are needed.en_US
dc.identifier.endpage549en_US
dc.identifier.issn0001-5458
dc.identifier.issue5en_US
dc.identifier.pmid17168267
dc.identifier.scopus2-s2.0-33751220496
dc.identifier.scopusqualityQ3
dc.identifier.startpage545en_US
dc.identifier.urihttps://hdl.handle.net/11468/20907
dc.identifier.volume106en_US
dc.identifier.wosWOS:000242091700014
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherActa Medical Belgicaen_US
dc.relation.ispartofActa Chirurgica Belgica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGangrenous Cholecystitisen_US
dc.subjectCholecystitisen_US
dc.titleFactors affecting morbidity and mortality in gangrenous cholecystitisen_US
dc.titleFactors affecting morbidity and mortality in gangrenous cholecystitis
dc.typeArticleen_US

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