Effect of cigarette smoking on nasal mucociliary transport rate: Rhinoscintigraphic evaluation with using 99mTc-macroaggregated albumin

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dc.contributor.authorDostbil, Zeki
dc.contributor.authorDag, Yusuf
dc.contributor.authorAbakay, Abdurrahman
dc.contributor.authorBakir, Salih
dc.contributor.authorSezgi, Cengizhan
dc.contributor.authorAbakay, Ozlem
dc.contributor.authorSen, Hadice
dc.date.accessioned2024-04-24T17:33:32Z
dc.date.available2024-04-24T17:33:32Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjectives: Cigarette smoking has harmful effects on mucociliary transport (MCT) in respiratory system. We aimed to investigate the association between nasal mucociliary transport rate (NMTR) and duration and amount of smoking in chronic cigarette smokers. Materials and Methods: Fifty four current cigarette smokers and 40 healthy non-smokers were included in this study. In all cases, we measured the NMTR using Tc-99m-macroaggregated albumin (Tc-99m-MAA) rhinoscintigraphy. Results: The mean NMTR of the smokers was lower than that of the healthy non-smoker controls (5.63 +/- 2.78; 9.44 +/- 2.09, respectively) (p<0.0001). There were not statistically significant correlation between NMTRs and year of smoking, and smoking pack-year in smokers (p>0.05; r=0.003, r=-0.2, respectively) whereas there was a statistically significant correlation between NMTRs and cigarettes per day in smokers (p=0.024; r=-0.307). Conclusions: Our findings demonstrated that cigarette smoking decreases the nasal NMTR in chronic term. Impaired mucociliary transport in respiratory system may have harmful effects on the human health. The degree of impairment in NMTRs in smokers may increase as the number of cigarettes per day increases.en_US
dc.identifier.endpage3462en_US
dc.identifier.issn1840-2291
dc.identifier.issue10en_US
dc.identifier.scopus2-s2.0-84871186009
dc.identifier.scopusqualityN/A
dc.identifier.startpage3458en_US
dc.identifier.urihttps://hdl.handle.net/11468/20735
dc.identifier.volume6en_US
dc.identifier.wosWOS:000312158300032
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherDrunpp-Sarajevoen_US
dc.relation.ispartofHealthmed
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTobacco Smokeen_US
dc.subjectSmokingen_US
dc.subjectMucociliary Clearanceen_US
dc.subjectRadionuclide Imagingen_US
dc.titleEffect of cigarette smoking on nasal mucociliary transport rate: Rhinoscintigraphic evaluation with using 99mTc-macroaggregated albuminen_US
dc.titleEffect of cigarette smoking on nasal mucociliary transport rate: Rhinoscintigraphic evaluation with using 99mTc-macroaggregated albumin
dc.typeArticleen_US

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