Effect of cigarette smoking on nasal mucociliary transport rate: Rhinoscintigraphic evaluation with using 99mTc-macroaggregated albumin
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Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Drunpp-Sarajevo
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objectives: Cigarette smoking has harmful effects on mucociliary transport (MCT) in respiratory system. We aimed to investigate the association between nasal mucociliary transport rate (NMTR) and duration and amount of smoking in chronic cigarette smokers. Materials and Methods: Fifty four current cigarette smokers and 40 healthy non-smokers were included in this study. In all cases, we measured the NMTR using Tc-99m-macroaggregated albumin (Tc-99m-MAA) rhinoscintigraphy. Results: The mean NMTR of the smokers was lower than that of the healthy non-smoker controls (5.63 +/- 2.78; 9.44 +/- 2.09, respectively) (p<0.0001). There were not statistically significant correlation between NMTRs and year of smoking, and smoking pack-year in smokers (p>0.05; r=0.003, r=-0.2, respectively) whereas there was a statistically significant correlation between NMTRs and cigarettes per day in smokers (p=0.024; r=-0.307). Conclusions: Our findings demonstrated that cigarette smoking decreases the nasal NMTR in chronic term. Impaired mucociliary transport in respiratory system may have harmful effects on the human health. The degree of impairment in NMTRs in smokers may increase as the number of cigarettes per day increases.
Açıklama
Anahtar Kelimeler
Tobacco Smoke, Smoking, Mucociliary Clearance, Radionuclide Imaging
Kaynak
Healthmed
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
6
Sayı
10
