Serum zinc and copper levels in southeastern Turkish children with giardiasis or amebiasis

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dc.contributor.authorKarakas, Z
dc.contributor.authorDemirel, N
dc.contributor.authorTarakcioglu, M
dc.contributor.authorMete, N
dc.date.accessioned2024-04-24T17:17:56Z
dc.date.available2024-04-24T17:17:56Z
dc.date.issued2001
dc.departmentDicle Üniversitesien_US
dc.description.abstractAlterations of serum zinc (Zn) and copper (Cu) concentrations are commonly found in patients suffering from gastrointestinal infections and with hepatic, renal, cardiovascular, and malignant diseases. In this study, the serum Zn and Cu levels in 20 children with giardiasis and in 40 children with amebiasis were evaluated. The serum Zn levels showed a significant decrease when compared to controls (p<0.001). After metronidazole therapy, a significant increase in Zn levels was observed (p<0.001). There was no significant difference in serum Cu levels between patients and controls before therapy. Before therapy, the serum Cu/Zn ratio in children with either giardiasis or amebiasis was significantly higher than that of the control group. After therapy, the Cu/Zn ratio was found to be back to normal. There were no significant differences in serum Zn levels and Cu/Zn ratios between children with and without diarrhea and there was no significant difference in children with or without failure to thrive. We concluded that Zn deficiency and elevated Cu/Zn ratio could be acute-phase responses to parasitic infections in children with giardiasis or amebiasis and that a successful treatment of the primary disorder will lead to complete recovery. Further studies are in progress to confirm the benefit of Zn supplementation during the acute phase of the disease, particularly in zinc-deficient regions of the world, such as in the case of Turkey.en_US
dc.identifier.doi10.1385/BTER:84:1-3:011
dc.identifier.endpage18en_US
dc.identifier.issn0163-4984
dc.identifier.issue1-3en_US
dc.identifier.pmid11817681
dc.identifier.scopus2-s2.0-0035674953
dc.identifier.scopusqualityQ1
dc.identifier.startpage11en_US
dc.identifier.urihttps://doi.org/10.1385/BTER:84:1-3:011
dc.identifier.urihttps://hdl.handle.net/11468/18443
dc.identifier.volume84en_US
dc.identifier.wosWOS:000173054200002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherHumana Press Incen_US
dc.relation.ispartofBiological Trace Element Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectZincen_US
dc.subjectCopperen_US
dc.subjectGiardiasisen_US
dc.subjectAmebiasisen_US
dc.subjectParasitic Infectionsen_US
dc.titleSerum zinc and copper levels in southeastern Turkish children with giardiasis or amebiasisen_US
dc.titleSerum zinc and copper levels in southeastern Turkish children with giardiasis or amebiasis
dc.typeArticleen_US

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