Both Systemic and Pulmonary Artery Stiffness Predict Ventricular Functional Recovery after Successful Percutaneous Closure of Atrial Septal Defects in Adults

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dc.contributor.authorBaykan, Ahmet Oytun
dc.contributor.authorGur, Mustafa
dc.contributor.authorAcele, Armagan
dc.contributor.authorSeker, Taner
dc.contributor.authorKalkan, Gulhan Yuksel
dc.contributor.authorSahin, Durmus Yildiray
dc.contributor.authorKoc, Mevlut
dc.date.accessioned2024-04-24T17:11:26Z
dc.date.available2024-04-24T17:11:26Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackgroundPercutaneous closure of atrial septal defect (ASD) has become the preferred method in treatment of the majority of cases. The aim of this study was to evaluate the echocardiographic effects of percutaneous closure of secundum ASD in adults and assess which parameters predict good response to closure. DesignWe prospectively included 42 patients with secundum ASD treated successfully with percutaneous device closure. All patients underwent transthoracic echocardiography examination with tissue Doppler imaging before, 24 hours after and within 3 months of intervention. Measurements of arterial stiffness were carried out using a Mobil-O-Graph arteriography system. ResultsRemodeling of heart chambers occurred immediately and persisted at 3 months after ASD closure. Significant decreases were observed in right ventricle (RV) end-diastolic diameter, right atrium volume index, and tricuspid annular plane systolic excursion both after the procedure and at 3 months (P<.01 for all). The RV and left ventricle (LV) tissue Doppler-myocardial performance index demonstrated to decline during follow up (P=.0001). Significant correlations were found between pulse-wave velocity, augmentation index, pulmonary artery stiffness, and LV-RV tissue Doppler-myocardial performance index at third month. Linear regression analyses showed that pulse-wave velocity is the most effective parameter of LV and pulmonary artery stiffness is the most effective parameter of RV functional recovery, respectively, assessed by tissue Doppler-myocardial performance index. ConclusionsPercutaneous closure of secundum ASD in adults has various sustained benefits on multiple echocardiographic parameters within 3 months. The changes in RV and LV function after device closure were significantly correlated with the degree of pulmonary artery stiffness and pulse-wave velocity, respectively.en_US
dc.identifier.doi10.1111/chd.12302
dc.identifier.endpage154en_US
dc.identifier.issn1747-079X
dc.identifier.issn1747-0803
dc.identifier.issue2en_US
dc.identifier.pmid26556671
dc.identifier.scopus2-s2.0-84949033302
dc.identifier.scopusqualityQ4
dc.identifier.startpage144en_US
dc.identifier.urihttps://doi.org/10.1111/chd.12302
dc.identifier.urihttps://hdl.handle.net/11468/17513
dc.identifier.volume11en_US
dc.identifier.wosWOS:000373681300007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTech Science Pressen_US
dc.relation.ispartofCongenital Heart Disease
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAtrial Septal Defecten_US
dc.subjectPercutaneous Closureen_US
dc.subjectVentricle Recoveryen_US
dc.subjectAortic Stiffnessen_US
dc.subjectPulmonary Artery Stiffnessen_US
dc.titleBoth Systemic and Pulmonary Artery Stiffness Predict Ventricular Functional Recovery after Successful Percutaneous Closure of Atrial Septal Defects in Adultsen_US
dc.titleBoth Systemic and Pulmonary Artery Stiffness Predict Ventricular Functional Recovery after Successful Percutaneous Closure of Atrial Septal Defects in Adults
dc.typeArticleen_US

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