Comparison of left ventricular functional parameters obtained from three different commercial automated software cardiac quantification program packages and their intraobserver reproducibility

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dc.contributor.authorDostbil, Zeki
dc.contributor.authorAriturk, Zuhal
dc.contributor.authorCil, Habib
dc.contributor.authorElbey, Mehmet Ali
dc.contributor.authorTekbas, Ebru
dc.contributor.authorYazici, Mehmet
dc.contributor.authorYildiz, Ismail
dc.date.accessioned2024-04-24T16:02:43Z
dc.date.available2024-04-24T16:02:43Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective ECG-gated myocardial perfusion scintigraphy (MPS) can be used to determine several cardiac functional parameters (e. g., left ventricular ejection fraction (LVEF), end-diastolic volume (EDV), and end-systolic volume (ESV)). In this study, we aimed to compare these cardiac functional parameters calculated by the following cardiac quantification programs: Emory Cardiac Toolbox (ECTb), Quantitative Gated SPECT (QGS), and Myometrix. We also evaluated reproducibility of the cardiac programs. Methods Fifty-seven patients (27 male, 30 female) at Elazig Research and Training Hospital from 2008 to 2009 were included in this study. In all patients, (99m)Tc-MIBI ECG-Gated (8-bin frame mode) myocardial perfusion scintigraphies were performed. By using 3 different cardiac quantification programs (ECTb, QGS, and Myometrix); LVEF, EDV, and ESV were calculated. The same raw data of MPS images were reprocessed at different time periods, and these 3 parameters were recalculated. LVEF, EDV, and ESV yielded by 3 different programs were compared for interprogram variability assessment, and parameters calculated at two different time periods were compared to evaluate intraprogram reproducibility. Results There were statistically significant differences between ECTb, QGS, and Myometrix programs for LVEF, EDV, and ESV (p < 0.001). There was also a statistically significant correlation between LVEF and EDV (p < 0.001, r = 0.546; p < 0.001, r = 0.45, respectively), but no statistically significant correlation was present between the ESV values (p > 0.05, r = 0.09). Statistically significant differences were not found between the values of LVEF, EDV, and ESV obtained from the first and second reconstruction analysis of 3 cardiac quantification programs. Discussion Different MPS cardiac software programs give variable (but correlated) LVEF and left ventricular volumetric measures. Those obtained from different cardiac softwares cannot be used interchangeably. Our findings have shown that ECTb, QGS, and Myometrix programs are reproducible, with respect to LVEF, EDV, and ESV.en_US
dc.identifier.doi10.1007/s12149-010-0435-1
dc.identifier.endpage131en_US
dc.identifier.issn0914-7187
dc.identifier.issue2en_US
dc.identifier.pmid21104169
dc.identifier.scopus2-s2.0-79954438473
dc.identifier.scopusqualityQ2
dc.identifier.startpage125en_US
dc.identifier.urihttps://doi.org/10.1007/s12149-010-0435-1
dc.identifier.urihttps://hdl.handle.net/11468/14890
dc.identifier.volume25en_US
dc.identifier.wosWOS:000288072600007
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofAnnals of Nuclear Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardiac Gated Specten_US
dc.subjectEctben_US
dc.subjectQgsen_US
dc.subjectMyometrixen_US
dc.titleComparison of left ventricular functional parameters obtained from three different commercial automated software cardiac quantification program packages and their intraobserver reproducibilityen_US
dc.titleComparison of left ventricular functional parameters obtained from three different commercial automated software cardiac quantification program packages and their intraobserver reproducibility
dc.typeArticleen_US

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