A simple method for the assessment of arterial stiffness in pre-eclamptic patients

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dc.contributor.authorOylumlu, Mustafa
dc.contributor.authorOylumlu, Muhammed
dc.contributor.authorYuksel, Murat
dc.contributor.authorYildiz, Abdulkadir
dc.contributor.authorBilik, Mehmet Zihni
dc.contributor.authorAkil, Mehmet Ata
dc.contributor.authorOzler, Ali
dc.date.accessioned2024-04-24T17:20:31Z
dc.date.available2024-04-24T17:20:31Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Arterial stiffness (AS), the term describes the rigidity of arterial walls, and its hemodynamic results have been shown to be associated with increase in future cardiovascular events. Women with pre-eclampsia in their past pregnancies have a higher risk of developing cardiovascular disease later in life. The goal of this study was to assess AS using a non-invasive and simple oscillometric method in pregnant women with and without pre-eclampsia. Methods: Ninety pregnant women, forty-five of which had pre-eclampsia, were included in the study. The vascular measurements were performed with a Mobil-O-Graph 24 h PWA Monitor, an automatic oscillometric device. Statistical analysis was performed using the Chi-square, independent sample t-test or the Mann-Whitney U test, Pearson correlation, and linear regression tests. Results: All the vascular function parameters were significantly higher in the patients with pre-eclampsia. The pulse wave velocity (PWV) values found in the pre-eclampsia group were positively correlated with gestational age, maternal age, glucose level, creatinine level, augmentation index, and central blood pressure. Using linear regression analysis, the PWV values were confirmed to be positively correlated with gestational age, maternal age, and central systolic blood pressure. The women with severe pre-eclampsia had significantly higher blood pressures, PWV values, augmentation indices, and cardiac outputs when compared with the patients with mild pre-eclampsia. Conclusion: Oscillometric PWV measurement is already accepted as the most reproducible quick, simple, and inexpensive non-invasive method for the assessment of large artery stiffness. It can be applied to evaluate the AS and also aid in detecting future cardiovascular risk of patients with pre-eclampsia.en_US
dc.description.sponsorshipDicle University DUBAPen_US
dc.description.sponsorshipThe authors report no conflicts of interest. We are grateful to Dicle University DUBAP for their sponsorship about English editing of this manuscript.en_US
dc.identifier.doi10.3109/10641963.2014.913608
dc.identifier.endpage537en_US
dc.identifier.issn1064-1963
dc.identifier.issn1525-6006
dc.identifier.issue8en_US
dc.identifier.pmid24786588
dc.identifier.scopus2-s2.0-84908610146
dc.identifier.scopusqualityQ2
dc.identifier.startpage531en_US
dc.identifier.urihttps://doi.org/10.3109/10641963.2014.913608
dc.identifier.urihttps://hdl.handle.net/11468/19109
dc.identifier.volume36en_US
dc.identifier.wosWOS:000344605600002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofClinical and Experimental Hypertension
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectArterial Stiffnessen_US
dc.subjectHypertensionen_US
dc.subjectOscillometric Methoden_US
dc.subjectPulse Wave Velocityen_US
dc.subjectPre-Eclampsiaen_US
dc.titleA simple method for the assessment of arterial stiffness in pre-eclamptic patientsen_US
dc.titleA simple method for the assessment of arterial stiffness in pre-eclamptic patients
dc.typeArticleen_US

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