Effectiveness of collagenase in the treatment of sacrococcygeal pilonidal sinus disease

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dc.contributor.authorAldemir, M
dc.contributor.authorKara, IH
dc.contributor.authorErten, G
dc.contributor.authorTaçyildiz, I
dc.date.accessioned2024-04-24T16:01:56Z
dc.date.available2024-04-24T16:01:56Z
dc.date.issued2003
dc.departmentDicle Üniversitesien_US
dc.description.abstractPurpose. Sacrococcygeal pilonidal sinus disease (SPSD) is a disease affecting young patients, which results in a long-term loss of productive power, and also tends to have high rates of morbidity since it has no ideal treatment. The main purpose of this study was to investigate the effectiveness of topical collagenase in the treatment of SPSD. Methods. In the present study, 40 patients admitted to our department were separated into two groups. Excision and marsupialization with dressing by bacterial collagenase was performed in the first group, while the treatment was excision and marsupialization without dressing by bacterial collagenase in the second group. Results. We determined that the healing in terms of the width and depth of the wound in the first week and in depth of wound in the second week was better in group I than in group 2 (P = 0.040, P = 0.020, P = 0.048, respectively). The duration of wound healing was 21.9 +/- 1.3 days in group 1, and 28.1 +/- 1.3 days in group 2 (P = 0.0001). The recurrence rate in the intergluteal area, which heals by granulation and has no hair follicles, tends to decrease when a partial closure is obtained. Conclusion. We therefore recommend an excision, marsupialization, and dressing with bacterial collagenase, in cases with noncomplicated SPSD.en_US
dc.identifier.doi10.1007/s005950300022
dc.identifier.endpage109en_US
dc.identifier.issn0941-1291
dc.identifier.issue2en_US
dc.identifier.pmid12616370
dc.identifier.scopus2-s2.0-0346666889
dc.identifier.scopusqualityQ1
dc.identifier.startpage106en_US
dc.identifier.urihttps://doi.org/10.1007/s005950300022
dc.identifier.urihttps://hdl.handle.net/11468/14516
dc.identifier.volume33en_US
dc.identifier.wosWOS:000181723500005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringer-Verlagen_US
dc.relation.ispartofSurgery Today
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSacrococcygeal Pilonidal Sinus Diseaseen_US
dc.subjectBacterial Collagenaseen_US
dc.subjectTreatmenten_US
dc.titleEffectiveness of collagenase in the treatment of sacrococcygeal pilonidal sinus diseaseen_US
dc.titleEffectiveness of collagenase in the treatment of sacrococcygeal pilonidal sinus disease
dc.typeArticleen_US

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