Comparison of Cytotoxicity of Four Different Adhesive Materials Before and After Polymerisation

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dc.contributor.authorCangul, Suzan
dc.contributor.authorAdiguzel, Ozkan
dc.contributor.authorTekin, Samet
dc.date.accessioned2024-04-24T17:20:45Z
dc.date.available2024-04-24T17:20:45Z
dc.date.issued2020
dc.departmentDicle Üniversitesien_US
dc.description.abstractIntroduction: The aim of this study was to make a quantitative comparison of the cytotoxic potentials of four different polymerised and unpolymerised self-etching adhesives which were newly used clinically. Materials and Methods: Cytotoxic effects of both polymerised and unpolymerised forms of all test adhesives were evaluated against L929 cell line using the MTT test. The activity for unpolymerised adhesives was assessed in different doses and incubation times manner. On the other hand, cytotoxicity of the polymerised adhesives prepared at different extraction times were evaluated as dependent on incubation times. Two-Way Variance Analysis and Bonferroni post-test was used for statistical evaluation. Results: There were statistically significant differences between the groups (p < 0.05). In general, it was shown that unpolymerised and polymerised forms of each of the test compounds exhibited a time-dependent cytotoxic effect. However, the effect on polymerised forms was found to be independent of the duration of the extraction, while the effect on the unpolymerised forms increased dose-dependently. It was also determined that the most cytotoxic material in the unpolymerised form was Dentsply and in the polymerised form was Tokuyama. Conclusions: Dentsply should be preferred over Tokuyama to be able to provide clinically long-lasting restorations.en_US
dc.identifier.doi10.3290/j.ohpd.a43940
dc.identifier.endpage51en_US
dc.identifier.issn1602-1622
dc.identifier.issn1757-9996
dc.identifier.issue1en_US
dc.identifier.pmid32051970
dc.identifier.scopus2-s2.0-85079336179
dc.identifier.scopusqualityQ1
dc.identifier.startpage43en_US
dc.identifier.urihttps://doi.org/10.3290/j.ohpd.a43940
dc.identifier.urihttps://hdl.handle.net/11468/19230
dc.identifier.volume18en_US
dc.identifier.wosWOS:000514443000007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherQuintessence Publishing Co Incen_US
dc.relation.ispartofOral Health & Preventive Dentistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdhesive Materialsen_US
dc.subjectCytotoxicityen_US
dc.subjectPolymerisationen_US
dc.subjectMtt Testen_US
dc.titleComparison of Cytotoxicity of Four Different Adhesive Materials Before and After Polymerisationen_US
dc.titleComparison of Cytotoxicity of Four Different Adhesive Materials Before and After Polymerisation
dc.typeArticleen_US

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