Surgical management of sporadic hemangioblastomas located in the posterior fossa of brain

Basit Öğe Kaydı
dc.contributor.authorBasar, Ibrahim
dc.contributor.authorOzturk, Pinar Aydin
dc.contributor.authorTuncer, Mehmet Cudi
dc.contributor.authorTuran, Yahya
dc.contributor.authorYilmaz, Tevfik
dc.date.accessioned2024-04-24T17:15:11Z
dc.date.available2024-04-24T17:15:11Z
dc.date.issued2021
dc.departmentDicle Üniversitesien_US
dc.description.abstractPurpose: Hemangioblastomas (HBs) are highly vascular tumors, constituting 2%-3% of central nervous system (CNS) tumors. Surgery is a treatment option for HBs. The purpose of this study was to evaluate the demographic, clinical, and radiological findings of patients with HBs who were operated on via microsurgical technique at our clinic and to determine the findings specific to HBs and evaluate their pathological findings and confirmation. Methods: We evaluated age, gender, initial complaints and duration of 100 patients (50 female and 50 male patients), presence of cranial nerve deficits, magnetic resonance imaging, data (localization, presence of hydrocephalus, tumor size, enhancement pattern, and cystic and solid component features), resection rates, pathological findings (grade, Ki-67 ratio, and staining results), recurrence, special conditions of patients, and the final status of patients in this study. Results: Mean age was 39.08 +/- 14.77 years and 66.7% of the patients presented with cerebellar findings. Five of the cases were located in the brainstem, five were located in the cerebellopontine angle, and two were in the cerebellar cortex. In all patients, gross total resection was performed using arteriovenous malformation repair. Conclusions: Surgical intervention of small and cystic tumors can be performed safely with en bloc resection along with preoperative detailed imaging, improved microsurgical techniques, and an extensive understanding of anatomical and vascular structures. On the contrary, patients with a brainstem invasion and solid structure present surgical difficulties due to arteriovenous malformation-like vascularizations; therefore, gross total resection is the optimal treatment in HBs.en_US
dc.identifier.doi10.12871/00039829202121
dc.identifier.endpage61en_US
dc.identifier.issn0003-9829
dc.identifier.issue2en_US
dc.identifier.pmid34184238
dc.identifier.scopus2-s2.0-85109641184
dc.identifier.scopusqualityQ4
dc.identifier.startpage51en_US
dc.identifier.urihttps://doi.org/10.12871/00039829202121
dc.identifier.urihttps://hdl.handle.net/11468/18365
dc.identifier.volume159en_US
dc.identifier.wosWOS:000705064800001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherPisa Univ Pressen_US
dc.relation.ispartofArchives Italiennes De Biologie
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHemangioblastomaen_US
dc.subjectPosterior Fossa Tumoren_US
dc.subjectBrain-Stem Tumoren_US
dc.titleSurgical management of sporadic hemangioblastomas located in the posterior fossa of brainen_US
dc.titleSurgical management of sporadic hemangioblastomas located in the posterior fossa of brain
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu