Evaluation of the Frequency of QTc Dispersion and Its Relationship with Clinical and Laboratory Parameters in Dialysis Patients
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Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turk Nefroloji Diyaliz Transplantasyon Dergisi
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
OBJECTIVE: QTc dispersion is defined as the difference between the maximal and minimal correct QT interval on standard 12-lead ECG. Increased QTc dispersion has been reported in ESRD patients. In our study, we aimed to evaluate the frequency of QTc dispersion and its relationship between clinical and laboratory parameters in patients on regular dialysis programme. MATERIAL and METHODS: Sixty patients underwent dialysis ( 30 HD, 30 CAPD) and another 30 healthy subjects were enrolled into the study. The standard 12 lead ECGs were performed and QTcd was measured from all dialysis patients and control subjects. Blood samples were collected for the measurement of laboratory parameters. RESULTS: Dialysis patients showed significantly higher QTcd than control subjects (55.75 +/- 36.48 versus 28.73 +/- 28.27; p=0.001). Patients with QTcd > 50 ms had significantly higher SBP, urea and ferritin levels, but significantly lower iron binding capacity and calcium levels compared those with QTcd <= 50 ms(p<0.05). Positive correlations were found between QTcd and urea, ferritin and SBP levels, and inverse correlations with iron binding capacity level (p<0.05). CONCLUSION: The frequency of QTc dispersion was 40% among the dialysis patients. Although serum calcium was significantly lower in patients who had QTcd > 50 ms than QTcd <= 50 ms (p<0.05), there was no significant correlation between QTcd and calcium.
Açıklama
Anahtar Kelimeler
Qtcd, Dialysis Patients, Arrhythmia, Electrocardiography, Calcium
Kaynak
Turkish Nephrology Dialysis and Transplantation Journal
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
22
Sayı
2
