The effect of pyridoxine supplementation on plasma lipoproteins and its relationship with atherogenic risk

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dc.contributor.authorSermet, A
dc.contributor.authorAtmaca, M
dc.contributor.authorDiken, H
dc.contributor.authorKelle, M
dc.contributor.authorDeniz, B
dc.date.accessioned2024-04-24T17:38:20Z
dc.date.available2024-04-24T17:38:20Z
dc.date.issued1999
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe effect of pyridoxine-HCl on cholesterol in plasma lipoprotein fractions and its relationship with atherogenic risk were investigated in mate Sprague-Dawley rats and healthy human volunteers. Plasma cholesterol, very low and low density lipoprotein cholesterol (VLDL-C and LDL-C) decreased, and high density lipoprotein cholesterol (HDL-C) increased, in rats treated with pyridoxine. Although the cholesterol content of the liver did not change, it decreased significantly in the aorta. Atherogenic risk decreased in rats treated with pyridoxine because of a decrease in the plasma/HDL or LDL/HDL cholesterol ratio and the aorta cholesterol. Plasma cholesterol and cholesterol in the lipoprotein fractions of healthy volunteers given a placebo did not change significantly at the end of the experimental period. Pyridoxine affected the plasma cholesterol and cholesterol in lipoproteins in healthy persons as well as in the rats. Plasma cholesterol, VLDL-C and LDL-C decreased while HDL-C increased. Thus, the atherogenic risk decreased significantly. These findings; indicate that pyridoxine may be an antiatherogenic agent.en_US
dc.identifier.endpage14en_US
dc.identifier.issn0961-088X
dc.identifier.issue231en_US
dc.identifier.scopus2-s2.0-0033241642
dc.identifier.scopusqualityN/A
dc.identifier.startpage7en_US
dc.identifier.urihttps://hdl.handle.net/11468/21410
dc.identifier.volume59en_US
dc.identifier.wosWOS:000080525900001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherFaculty Pressen_US
dc.relation.ispartofBiomedical Letters
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPyridoxine-Hclen_US
dc.subjectCholesterolen_US
dc.subjectLipoproteinsen_US
dc.subjectAtherogenic Risken_US
dc.titleThe effect of pyridoxine supplementation on plasma lipoproteins and its relationship with atherogenic risken_US
dc.titleThe effect of pyridoxine supplementation on plasma lipoproteins and its relationship with atherogenic risk
dc.typeArticleen_US

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