DNA CLEAVAGE PROTECTING ACTIVITY AND IN VITRO ANTIOXIDANT POTENTIAL OF AQUEOUS EXTRACT FROM FRESH STEMS OF RHEUM RIBES

Basit Öğe Kaydı
dc.contributor.authorTanrikut, S. Emen
dc.contributor.authorCeken, B.
dc.contributor.authorAltas, S.
dc.contributor.authorPirinccioglu, M.
dc.contributor.authorKizil, G.
dc.contributor.authorKizil, M.
dc.date.accessioned2024-04-24T17:18:05Z
dc.date.available2024-04-24T17:18:05Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractRheum ribes L. (Polygonaceae) is a common species of rhubarb in Turkey, which is also found in Iraq, Iran, Pakistan, Afghanistan, and Russia. The antioxidant potency of stems was investigated employing various in vitro systems, such as lipid peroxidation in rat brain homogenate, 1,1-diphenyl-2-picrylhydrazyl (DPPH) and superoxide anion radical scavenging, ferric reducing power, metal chelation activity. R. ribes stem parts showed strong inhibitory activity toward lipid peroxidation of rat brain homogenate induced by the FeCl3-ascorbic acid system. R. ribes extract was able to reduce the stable free radical DPPH 83.9+/-1.90% at 150 mu g ml(-1). The reducing power of the extract was 0.46+/-0.074 at 250 mu g ml(-1). The effect of extract of R. ribes on DNA cleavage induced by UV-photolysis of H2O2 using pBluescript M13+ plasmid DNA was also investigated. This extract significantly inhibited DNA damage induced by reactive oxygen species (ROS). These findings demonstrate that aqueous extract from fresh stems of R. ribes has antioxidant activity and thus have great potential as a source for natural health products.en_US
dc.identifier.doi10.1556/AAlim.42.2013.4.1
dc.identifier.endpage472en_US
dc.identifier.issn0139-3006
dc.identifier.issn1588-2535
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84889857561
dc.identifier.scopusqualityQ3
dc.identifier.startpage461en_US
dc.identifier.urihttps://doi.org/10.1556/AAlim.42.2013.4.1
dc.identifier.urihttps://hdl.handle.net/11468/18591
dc.identifier.volume42en_US
dc.identifier.wosWOS:000327799900001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherAkademiai Kiado Zrten_US
dc.relation.ispartofActa Alimentaria
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRhubarben_US
dc.subjectRheum Ribesen_US
dc.subjectAntioxidant Activityen_US
dc.subjectDna Cleavageen_US
dc.subjectEdible Planten_US
dc.titleDNA CLEAVAGE PROTECTING ACTIVITY AND IN VITRO ANTIOXIDANT POTENTIAL OF AQUEOUS EXTRACT FROM FRESH STEMS OF RHEUM RIBESen_US
dc.titleDNA CLEAVAGE PROTECTING ACTIVITY AND IN VITRO ANTIOXIDANT POTENTIAL OF AQUEOUS EXTRACT FROM FRESH STEMS OF RHEUM RIBES
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu