A detailed study on the chemical and biological profiles of essential oil and methanol extract of Thymus nummularius (Anzer tea): Rosmarinic acid

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dc.contributor.authorErtas, Abdulselam
dc.contributor.authorBoga, Mehmet
dc.contributor.authorYilmaz, Mustafa Abdullah
dc.contributor.authorYesil, Yeter
dc.contributor.authorTel, Gulsen
dc.contributor.authorTemel, Hamdi
dc.contributor.authorHasimi, Nesrin
dc.date.accessioned2024-04-24T16:14:56Z
dc.date.available2024-04-24T16:14:56Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe aim of this study was to determine the chemical profile of Thymus nummularius by LC-MS/MS and GC/MS. Additionally, the methanol extract, essential oil and some individual main compounds of Thymus nummularius were tested for antioxidant, anticholinesterase and antimicrobial activities. Besides, HPLC-FLD was used to determine total aflatoxin in the plant material. Among the twenty-seven compounds studied by LC-MS/MS, rosmarinic acid (131,898.9 +/- 6463.0 mu g/g dry-extract) was found to be the most abundant compound in the methanol extract. On the other hand, thymol (60.38%) and terpinyl-acetate (10.49%) were found to be the major compounds of the essential oil. Both the essential oil and the methanol extract of T. nummularius exhibited strong antioxidant activity in the four tested methods. Furthermore, the essential oil showed high inhibitory activity against acetyl-,butyryl-cholinesterase enzymes and very strong antimicrobial activity against all tested microorganisms. Besides, T. nummularius can be used both as rosmarinic acid source and as food supplement due to its non-aflatoxin content and high antioxidant, anticholinesterase and antimicrobial activities. (C) 2015 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipDicle University Science and Technology Research and Application Center (DUBTAM); Dicle University [DUBAP: 14-EZF-69]en_US
dc.description.sponsorshipThe authors are thankful to Dicle University Science and Technology Research and Application Center (DUBTAM) for its support in this study. We acknowledge the Dicle University for financial support (Research University Grant DUBAP: 14-EZF-69).en_US
dc.identifier.doi10.1016/j.indcrop.2015.01.064
dc.identifier.endpage345en_US
dc.identifier.issn0926-6690
dc.identifier.issn1872-633X
dc.identifier.scopus2-s2.0-84922615559
dc.identifier.scopusqualityQ1
dc.identifier.startpage336en_US
dc.identifier.urihttps://doi.org/10.1016/j.indcrop.2015.01.064
dc.identifier.urihttps://hdl.handle.net/11468/15532
dc.identifier.volume67en_US
dc.identifier.wosWOS:000352039600046
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofIndustrial Crops and Products
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectThymus Nummulariusen_US
dc.subjectRosmarinic Aciden_US
dc.subjectAntioxidanten_US
dc.subjectAnticholinesteraseen_US
dc.subjectAntimicrobialen_US
dc.subjectEssential Oilen_US
dc.titleA detailed study on the chemical and biological profiles of essential oil and methanol extract of Thymus nummularius (Anzer tea): Rosmarinic aciden_US
dc.titleA detailed study on the chemical and biological profiles of essential oil and methanol extract of Thymus nummularius (Anzer tea): Rosmarinic acid
dc.typeArticleen_US

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