Nasal septum perforation in the patients with advanced breast cancer due to the treatment of lapatinib+capecitabine

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dc.contributor.authorOruc, Zeynep
dc.contributor.authorKucukoner, Mehmet
dc.contributor.authorUrakci, Zuhat
dc.contributor.authorKaplan, M. Ali
dc.contributor.authorSolmaz, Ihsan
dc.contributor.authorIsikdogan, Abdurrahman
dc.date.accessioned2024-04-24T17:27:44Z
dc.date.available2024-04-24T17:27:44Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractNasal septum perforation is a rare complication that can occur due to certain antineoplastic agents, especially antiangiogenic agents such as bevacizumab. There has been no case of nasal perforation case due to the treatment of lapatinib+capecitabine so far. Our case is nasal septum perforation occuring with the 38-year-old patient diagnosed with premenopausal advanced breast cancer during the treatment of lapatinib+capecitabine. It occured as epistaxis in the 30th month of patient's treatment. In the anterior rhinoscopy, nasal septum perforation was diagnosed. The patient had no nasal irritant or cocaine, or no trauma story. Although it is a rare complication, perforation due to lapatinib+capecitabine should be considered in the advanced breast cancer patients with the treatment of lapatinib+capecitabine when nasal symptoms (epistaxis, nasal congestion, local pain, irritation, rhinorrhea) occur.en_US
dc.identifier.doi10.5505/tjoncol.2015.1233
dc.identifier.endpage24en_US
dc.identifier.issn1300-7467
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84928635976en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage21en_US
dc.identifier.urihttps://doi.org/10.5505/tjoncol.2015.1233
dc.identifier.urihttps://hdl.handle.net/11468/20171
dc.identifier.volume30en_US
dc.identifier.wosWOS:000362108300004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isotren_US
dc.publisherKare Publen_US
dc.relation.ispartofTurk Onkoloji Dergisi-Turkish Journal of Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCapecitabineen_US
dc.subjectLapatiniben_US
dc.subjectNasal Septum Perforationen_US
dc.titleNasal septum perforation in the patients with advanced breast cancer due to the treatment of lapatinib+capecitabineen_US
dc.typeArticleen_US

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