Massive Pulmonary Embolism with Mobile Right Atrial Thrombus in a Pregnant Patient Using Valproic Acid

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dc.contributor.authorSoydinc, Hatice Ender
dc.contributor.authorYuce, Murat
dc.contributor.authorSari, Emine
dc.contributor.authorYavuz, Sema
dc.contributor.authorSari, Ibrahim
dc.contributor.authorDavutoglu, Vedat
dc.contributor.authorYigiter, Remzi
dc.date.accessioned2024-04-24T17:27:28Z
dc.date.available2024-04-24T17:27:28Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractPulmonary embolism is a life threatening condition. Pregnancy is among the risk factors of pulmonary embolism. There is reluctance about using thrombolytics s during pregnancy due to potential teratogenic effects. Valproic acid is one of the most commonly used antiepileptic agents, hovewer, its use during pregnancy is controversial because of the teratogenic potential. Among adverse effects of valproic acid use, elevated liver enzymes, thrombocytopenia have been reported. Moreover, product literature warns that pregnant women using valproic acid should be monitored for low fibrinogen and platelets and the potential for bleeding. The present case report describes successful treatment of a massive pulmonary embolism with tissue plasminogen activator (t-PA), caused by a mobile right atrial thrombus in a 30-year-old first trimester pregnant women using valproic acid. This has not been reported previously. During follow-ups, she was free of any signs or symptoms and gave birth to a baby by spontaneous vaginal delivery. The baby was completely healthy without any problem or deformity.en_US
dc.identifier.doi10.5152/jaem.2011.048
dc.identifier.endpage54en_US
dc.identifier.issn2149-5807
dc.identifier.issn2149-6048
dc.identifier.issue1en_US
dc.identifier.startpage52en_US
dc.identifier.trdizinid138828en_US
dc.identifier.urihttps://doi.org/10.5152/jaem.2011.048
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/138828
dc.identifier.urihttps://hdl.handle.net/11468/19957
dc.identifier.volume11en_US
dc.identifier.wosWOS:000420166900012en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofEurasian Journal of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPulmonary Embolismen_US
dc.subjectPregnanten_US
dc.subjectValproic Aciden_US
dc.subjectRight Atriumen_US
dc.subjectThrombolyticen_US
dc.titleMassive Pulmonary Embolism with Mobile Right Atrial Thrombus in a Pregnant Patient Using Valproic Aciden_US
dc.typeArticleen_US

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