Use of a decreased dose of cabergoline to treat secondary anoestrus in bitches

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dc.contributor.authorCirit, Uemuet
dc.contributor.authorBacinoglu, Suleyman
dc.contributor.authorTas, Muzaffer
dc.contributor.authorAlkan, Serhat
dc.date.accessioned2024-04-24T17:40:00Z
dc.date.available2024-04-24T17:40:00Z
dc.date.issued2007
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe aim of the study was to determine whether a dose (0.6 mu g/kg/d) quite lower than the prolactin-lowering dose of cabergoline, prepared for humans, would be a safe and effective method for the stimulation of oestrus in bitches at secondary anoestrus or late anoestrus. Twenty-four pure blood bitches from various breeds were used in the study at their already determined periods of anoestrus. The treatment group included bitches at late and prolonged anoestrus. Eight bitches that had not shown any signs of oestrus for the preceding 370 to 485 d formed the secondary anoestrus group. Eight of the 16 bitches at late anoestrus (days 165-280) have accomplished the late anoestrus group and another 8 have been chosen randomly for the control group (untreated). Cabergoline was orally administrated until day 2 after the onset of pro-oestrus or for a maximum of 42 d. Blood samples were taken daily from each bitch during the first 5 d of behavioural oestrus to measure progesterone concentrations. In the secondary anoestrus and late anoestrus groups, oestrus was induced on days 4-14 and 12-45 at a ratio of 75.0% (6/8) and 87.5% (7/8), respectively.. The mean pro-oestrus and behavioural oestrus durations, serum progesterone concentrations on day 5 of oestrus, ovulation rates, pregnancy rates, and the mean litter sizes in secondary anoestrus, late anoestrus, and control groups were found to be similar. None of the dogs had any adverse gastrointestinal effects associated with cabergoline administration. The results of the present study suggest that the administration of 0.6 mu g/kg/d of cabergoline is a safe and effective treatment for secondary anoestrus in bitches.en_US
dc.identifier.endpage46en_US
dc.identifier.issn0042-4870
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-34250633452
dc.identifier.scopusqualityN/A
dc.identifier.startpage43en_US
dc.identifier.urihttps://hdl.handle.net/11468/21520
dc.identifier.volume51en_US
dc.identifier.wosWOS:000245488100008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherNatl Veterinary Research Insten_US
dc.relation.ispartofBulletin of The Veterinary Institute in Pulawy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBitchen_US
dc.subjectSecondary Anoestrusen_US
dc.subjectLate Anoestrusen_US
dc.subjectOestrus Inductionen_US
dc.subjectCabergolineen_US
dc.titleUse of a decreased dose of cabergoline to treat secondary anoestrus in bitchesen_US
dc.titleUse of a decreased dose of cabergoline to treat secondary anoestrus in bitches
dc.typeArticleen_US

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