Neurological presentations of nutritional vitamin B12 deficiency in 42 breastfed infants in Southeast Turkey

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dc.contributor.authorTaskesen, Mustafa
dc.contributor.authorYaramis, Ahmet
dc.contributor.authorKatar, Selahattin
dc.contributor.authorGozu, Ayfer
dc.contributor.authorPirinccioglu, Ayfer Gozu
dc.contributor.authorSoker, Murat
dc.date.accessioned2024-04-24T17:21:07Z
dc.date.available2024-04-24T17:21:07Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim: Nutritional vitamin B12 deficiency is common in developing and underdeveloped countries and has a wide variety of neurological presentations. The aim of this study was to evaluate the neurological characteristics and laboratory results of infants with vitamin B12 deficiency. Materials and methods: A total of 42 infants were included in this study. All patients were evaluated for clinical, physical, and neurological abnormalities, and an attempt was made to obtain short-term neurologic follow-up. Results: Of 42 patients, 24 (57%) were boys and 18 (43%) were girls. The average age at diagnosis was 13.04 +/- 5.68 months. Most of these infants were breastfed only and born from mothers with inadequate animal-derived protein consumption. Hypotonia (100%), anorexia (92.8%), neurodevelopmental (85.7%), and social (80.9%) retardation were the most present symptoms in all infants. Conclusion: Severe neurological and hematological findings may be found in children with vitamin B12 deficiency. Early diagnosis and treatment is crucial in cases of hematological complications and neurologic impairment. Neurologic impairment may be irreversible if the diagnosis is delayed beyond 12 months. We think that dietary management, such as nutritional support with vitamin B12 for the mothers during pregnancy and complementary food for infants, may prevent the neurological deficits and neurodevelopmental retardation.en_US
dc.identifier.doi10.3906/sag-1009-1137
dc.identifier.endpage1096en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-80155129012en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1091en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1009-1137
dc.identifier.urihttps://hdl.handle.net/11468/19375
dc.identifier.volume41en_US
dc.identifier.wosWOS:000298197700020
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNeurological Presentationen_US
dc.subjectHypotoniaen_US
dc.subjectNutritionen_US
dc.subjectVitamin B12 Deficiencyen_US
dc.subjectInfancyen_US
dc.titleNeurological presentations of nutritional vitamin B12 deficiency in 42 breastfed infants in Southeast Turkeyen_US
dc.typeArticleen_US

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