Düşük ejeksiyon fraksiyonlu hastalarda koroner bypass uygulamaları: preoperatif, intraoperatif ve postoperatif verilerin incelenmesi
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Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Dicle Üniversitesi Tıp Fakültesi
Erişim Hakkı
Attribution-NonCommercial 3.0 United States
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess
Özet
Amaç: Sol ventrikül disfonsiyonu hastane mortalitesini etkileyen önemli bir faktördür. Aynı zamanda bu hastaların cerrahisi de yüksek risklidir. Bu çalışmada kliniğimizde düşük ejeksiyon fraksiyonuna sahip hastalara uygulanan pompalı veya pompasız miyokartiyal revaskularizasyonların klinik sonuçları değerlendirmeyi amaçladık. Yöntemler: Ejeksiyon fraksiyonu (EF) %40 ve altında olan 129 hasta retrospektif olarak incelendi. Çeşitli değişkenler (preoperatif, intraoperatif ve postoperatif) karşılaştırıldı. Hastaların preoperatif, peroperatif ve postoperatif inotropik destek alıp almadıkları da değerlendirildi.
Bulgular: Hastaların 84’ü (% 65,1) erkek,’ u bayan, yaş ortalaması 65,37 ± 8,49 olarak tespit edildi. Ortalama bazal metabolizma indeksi 26,33 ± 4,21 olarak bulundu. Hastaların EF’ lerinin dağılımı; 74 hastada (%57,4) EF si %40-36 arasında, 38 hastada (%29,5) EF si %35-31 arasında ve 17 hastada (%13,2) EF si ≤%30 şeklindeydi. NYHA Class ortalama 2,16 ± 1,03 olarak bulundu. Ortalama hasta başına düşen bypass sayısı 3,46 şeklinde belirlendi ve %92,2 hastada sol internal mammarian arter
kullanıldı. Hastane mortalitesi 5 (%3,9) olarak tespit edildi. En önemli sebepler kardiyak faktörler ya da eşlik eden multiorgan yetmezliğiydi. Postoperatif aritmiler en sık izlenen komplikasyondu. Sonuç: Düşük sol ventrikül fonksiyonuna sahip hastalar pompalı ya da pompasız miyokartiyal revaskülarizasyondan fayda görmekle birlikte mortalite riski normal ventrikül fonksiyonuna sahip hastaların riskinden daha fazladır. Ancak, tüm risklere rağmen deneyimli deneyimli ellerde bu hastalar da başarıyla ameliyat edilebilmektedir.
Objective: Left ventricle dysfunction is an important determinant that effects hospital mortality. At the same time, the surgery of these patients is also highly risky. In this study we aimed to evaluate the clinical outcomes of onpump or off-pump revascularizations in patients with low ejection fraction. Methods: One hundred and twenty-nine patients who have ≤ 40% ejection fraction (EF) was scanned retrospectively. Various variables were (preoperative, intraoperative, postoperative) were compared. It was evaluated that whether patients gets preoperative, intraoperative, postoperative support or not. Results: Eighty-four (65.1%) male and 45 (34.9%) female patient were detected with main age of 65.37 ± 8.49 years. Mean basal metabolism index was detected as 26.33 ± 4.21. The distrubution of EF of patients were as follows; EF is between %40-36 in 74 (57.4%) patients, EF is between %35-31 in 38 (29.5%) patients, and EF is ≤%30 in 17 (13.2%) patients. Mean NYHA Class was detected as 2.16 ± 1.03. Mean bypass count was determined as 3.46 per patient and left internal mammarian artery was used in 92.2% of the patients. Hospital mortality was detected as 5 (3.9%). The main important reasons were cardiac factors or concomitant multiorgan failure. Postoperatvie arrythmias were the most detected complications. Conclusion: The patients who have low left ventricular pump function are benefits myocardial revascularization, although mortality is higher than normal ventricular function. However, inspite the all risk, these patients can be sucessfully operated with experinced hands.
Objective: Left ventricle dysfunction is an important determinant that effects hospital mortality. At the same time, the surgery of these patients is also highly risky. In this study we aimed to evaluate the clinical outcomes of onpump or off-pump revascularizations in patients with low ejection fraction. Methods: One hundred and twenty-nine patients who have ≤ 40% ejection fraction (EF) was scanned retrospectively. Various variables were (preoperative, intraoperative, postoperative) were compared. It was evaluated that whether patients gets preoperative, intraoperative, postoperative support or not. Results: Eighty-four (65.1%) male and 45 (34.9%) female patient were detected with main age of 65.37 ± 8.49 years. Mean basal metabolism index was detected as 26.33 ± 4.21. The distrubution of EF of patients were as follows; EF is between %40-36 in 74 (57.4%) patients, EF is between %35-31 in 38 (29.5%) patients, and EF is ≤%30 in 17 (13.2%) patients. Mean NYHA Class was detected as 2.16 ± 1.03. Mean bypass count was determined as 3.46 per patient and left internal mammarian artery was used in 92.2% of the patients. Hospital mortality was detected as 5 (3.9%). The main important reasons were cardiac factors or concomitant multiorgan failure. Postoperatvie arrythmias were the most detected complications. Conclusion: The patients who have low left ventricular pump function are benefits myocardial revascularization, although mortality is higher than normal ventricular function. However, inspite the all risk, these patients can be sucessfully operated with experinced hands.
Açıklama
Anahtar Kelimeler
Düşük ejeksiyon fraksiyonu, Koroner bypass, Mortalite, İnotropik destek, Low ejection fraction, Coronary bypass, Mortality, İnotropic support
Kaynak
Dicle Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
41
Sayı
3
Künye
Karahan, O., Demirtaş, S., Sanrı, U.S., Atlı, F.H., Çalışkan, A., Yavuz, C. ve diğerleri. (2014). Düşük ejeksiyon fraksiyonlu hastalarda koroner bypass uygulamaları: preoperatif, intraoperatif ve postoperatif verilerin incelenmesi. Dicle Tıp Dergisi, 41(3), 463-467.
